PTSD and Physical Health

Overview

Journal Curr Psychiatry Rep

Publisher Current Science

Specialty Psychiatry

Date 2018 Oct 28

PMID 30367276

Citations 43

Authors

Annie L Ryder

Patrick M Azcarate

Beth E Cohen

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: We review evidence linking PTSD to physical health symptoms and specific disorders, highlighting areas with multiple studies and objective measures of disease states when available. We also examine evidence for biological, behavioral, and psychosocial mechanisms underlying these associations and discuss the clinical implications of recent research.

Recent Findings: Recent meta-analyses have found that evidence is particularly strong for increased risk of cardiovascular, metabolic, and musculoskeletal disorders among patients with PTSD. Numerous studies have found alterations in the hypothalamic-pituitary-adrenal axis, sympathetic nervous system, inflammation, and health behaviors that could increase risk of illness, but few studies have simultaneously incorporated measures of mechanisms and disease outcomes. Future research should focus on expanding the diversity of populations studied, particularly with respect to underrepresented racial and ethnic groups. Longitudinal studies that incorporate repeated measures of PTSD, pathogenic mechanisms of disease, and physical health outcomes and the addition of physical health outcomes to PTSD treatment trials will be most informative for the field.

Citing Articles

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.

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Cannabidiol Modulates Neuroinflammatory Markers in a PTSD Model Conducted on Female Rats.

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Protocol for remote Tai Chi and wellness for PTSD and pain in veterans.

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Assessing acceptance and feasibility of a conversational agent to support individuals living with post-traumatic stress disorder.

Han H, Mendu S, Jaworski B, Owen J, Abdullah S Digit Health. 2024; 10:20552076241286133.

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Epigenetics of violence against women: a systematic review of the literature.

Bailo P, Piccinini A, Barbara G, Caruso P, Bollati V, Gaudi S Environ Epigenet. 2024; 10(1):dvae012.

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