ETCM: an Encyclopaedia of Traditional Chinese Medicine

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2018 Oct 27

PMID 30365030

Citations 339

Authors

Hai-Yu Xu

Yan-Qiong Zhang

Zhen-Ming Liu

Tong Chen

Chuan-Yu Lv

Shi-Huan Tang

Xiao-Bo Zhang

Wei Zhang

Zhi-Yong Li

Rong-Rong Zhou

Hong-Jun Yang

Xiu-Jie Wang

Lu-Qi Huang

Affiliations

Soon will be listed here.

Abstract

Traditional Chinese medicine (TCM) is not only an effective solution for primary health care, but also a great resource for drug innovation and discovery. To meet the increasing needs for TCM-related data resources, we developed ETCM, an Encyclopedia of Traditional Chinese Medicine. ETCM includes comprehensive and standardized information for the commonly used herbs and formulas of TCM, as well as their ingredients. The herb basic property and quality control standard, formula composition, ingredient drug-likeness, as well as many other information provided by ETCM can serve as a convenient resource for users to obtain thorough information about a herb or a formula. To facilitate functional and mechanistic studies of TCM, ETCM provides predicted target genes of TCM ingredients, herbs, and formulas, according to the chemical fingerprint similarity between TCM ingredients and known drugs. A systematic analysis function is also developed in ETCM, which allows users to explore the relationships or build networks among TCM herbs, formulas,ingredients, gene targets, and related pathways or diseases. ETCM is freely accessible at http://www.nrc.ac.cn:9090/ETCM/. We expect ETCM to develop into a major data warehouse for TCM and to promote TCM related researches and drug development in the future.

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