MALT Lymphoma: Epidemiology, Clinical Diagnosis and Treatment

Overview

Journal J Med Life

Specialty General Medicine

Date 2018 Oct 27

PMID 30364585

Citations 45

Authors

Petruta Violeta Filip

Denisa Cuciureanu

Laura Sorina Diaconu

Ana Maria Vladareanu

Corina Silvia Pop

Affiliations

Soon will be listed here.

Abstract

Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas.

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