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Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson's Disease

Overview
Journal Mov Disord Clin Pract
Publisher Wiley
Specialty Neurology
Date 2018 Oct 27
PMID 30363559
Citations 21
Authors
Alessandra Fanciulli
Georg Goebel
Bernhard Metzler
Fabienne Sprenger
Werner Poewe
Gregor K Wenning
Klaus Seppi
Affiliations
Soon will be listed here.
Abstract

Background And Methods: To investigate the possible efficacy of an elastic abdominal binder to control orthostatic hypotension (OH) associated with Parkinson's disease (PD), 15 patients with PD and OH were enrolled in a single-blind crossover study with elastic abdominal versus placebo binder on two different days, separated by a 1-day interval, followed by a 4-week open-label follow-up.

Results: Intervention significantly reduced blood pressure fall upon tilting. The mean difference (standard deviation; 95% confidence intervals) between abdominal binder versus placebo was +10 mm Hg (10.2; +3.5, +16.5; = 0.006). No significant effect on supine mean blood pressure values was observed compared to placebo ( = 0.3). Symptoms of OH decreased significantly during follow-up ( = 0.003), as assessed by means of the Orthostatic Hypotension Questionnaire.

Conclusions: Our findings suggest that elastic abdominal binders may be a simple complementary tool to alleviate OH in PD.

Citing Articles

Neurogenic Orthostatic Hypotension in Parkinson Disease-A Narrative Review of Diagnosis and Management.

Grosu C, Noea O, Mastaleru A, Ignat E, Leon M J Clin Med. 2025; 14(2).

PMID: 39860637 PMC: 11765550. DOI: 10.3390/jcm14020630.

Diagnosis and treatment of autonomic failure, pain and sleep disturbances in Parkinson's disease: guideline "Parkinson's disease" of the German Society of Neurology.

Fanciulli A, Sixel-Doring F, Buhmann C, Krismer F, Hermann W, Winkler C J Neurol. 2025; 272(1):90.

PMID: 39751950 PMC: 11698777. DOI: 10.1007/s00415-024-12730-5.

A Safety-Centric Study on the Use of Inflatable Abdominal Binders for Managing Orthostatic Hypotension.

Toma M, Jose R, Syed F, Devine T Clin Pract. 2024; 14(5):1737-1743.

PMID: 39311288 PMC: 11417920. DOI: 10.3390/clinpract14050138.

Mechanism-based therapy of non-cardiac syncope: a practical guide.

Brignole M, Rivasi G, Fedorowski A Europace. 2024; 26(4).

PMID: 38529800 PMC: 10988836. DOI: 10.1093/europace/euae073.

Non-Pharmacological Treatment of Autonomic Dysfunction in Parkinson's Disease and Other Synucleinopathies.

Palma J, Thijs R J Parkinsons Dis. 2023; 14(s1):S81-S92.

PMID: 37694308 PMC: 11380254. DOI: 10.3233/JPD-230173.

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