Successful Transarterial Embolization with Cellulose Porous Beads for Occipital Haemangioma in an Infant with Kasabach-Merritt Syndrome

Overview

Journal BJR Case Rep

Publisher Oxford University Press

Specialty Radiology

Date 2018 Oct 27

PMID 30363243

Citations 2

Authors

Zaw Aung Khant

Toshinori Hirai

Osamu Ikeda

Eiji Furukoji

Yoshihito Kadota

Minako Azuma

Norihiro Shinkawa

Keiji Kitatani

Yoichi Mizutani

Kimihiko Endo

Yasuyuki Yamashita

Affiliations

Soon will be listed here.

Abstract

We report a 3-month-old boy with Kasabach-Merritt Syndrome (KMS) with an occipital haemangioma who underwent successful transarterial embolization (TAE) with cellulose porous beads (CPBs). As his response to steroids and coil embolization was inadequate, we performed TAE with CPBs, carefully preventing their migration via dangerous anastomoses. The tumour blush decreased, there were no complications, all coagulation tests were immediately normalized and the tumor size decreased gradually. TAE with CPBs is useful for the treatment of KMS.

Citing Articles

Efficacy of transcatheter arterial chemoembolization combined with sirolimus for treating Kasabach-Merritt phenomenon in infants, a retrospective study.

Yin C, Qi W, Wang S, Pan D, Chen X, Li S Ann Med. 2023; 55(1):2196090.

PMID: 37038342 PMC: 10101661. DOI: 10.1080/07853890.2023.2196090.

Effective surgical treatment of life-threatening huge vascular anomalies associated with thrombocytopenia and coagulopathy in infants unresponsive to drug therapy.

Wu Y, Qiu R, Zeng L, Liang L, Zhang J, Zhou J BMC Pediatr. 2020; 20(1):187.

PMID: 32340603 PMC: 7187498. DOI: 10.1186/s12887-020-02093-x.

References

Kai Y, Hamada J, Morioka M, Yano S, Nakamura H, Makino K . Clinical evaluation of cellulose porous beads for the therapeutic embolization of meningiomas. AJNR Am J Neuroradiol. 2006; 27(5):1146-50. PMC: 7975727. View

Hamada J, Kai Y, Nagahiro S, Hashimoto N, Iwata H, Ushio Y . Embolization with cellulose porous beads, II: Clinical trial. AJNR Am J Neuroradiol. 1996; 17(10):1901-6. PMC: 8337550. View

Kwok-Williams M, Perez Z, Squire R, Glaser A, Bew S, Taylor R . Radiotherapy for life-threatening mediastinal hemangioma with Kasabach-Merritt syndrome. Pediatr Blood Cancer. 2006; 49(5):739-44. DOI: 10.1002/pbc.20767. View

Wolfe S, Farhat H, Elhammady M, Moftakhar R, Aziz-Sultan M . Transarterial embolization of a scalp hemangioma presenting with Kasabach-Merritt syndrome. J Neurosurg Pediatr. 2009; 4(5):453-7. DOI: 10.3171/2009.6.PEDS08363. View

Acharya S, Pillai K, Francis A, Criton S, Parvathi V . Kasabach merritt syndrome: management with interferon. Indian J Dermatol. 2010; 55(3):281-3. PMC: 2965921. DOI: 10.4103/0019-5154.70705. View

Wang P, Zhou W, Tao L, Zhao N, Chen X . Clinical analysis of Kasabach-Merritt syndrome in 17 neonates. BMC Pediatr. 2014; 14:146. PMC: 4088914. DOI: 10.1186/1471-2431-14-146. View

Hamada J, Ushio Y, Kazekawa K, Tsukahara T, Hashimoto N, Iwata H . Embolization with cellulose porous beads, I: An experimental study. AJNR Am J Neuroradiol. 1996; 17(10):1895-9. PMC: 8337533. View

Bilbao J, Martinez-Cuesta A, Urtasun F, Cosin O . Complications of embolization. Semin Intervent Radiol. 2011; 23(2):126-42. PMC: 3036371. DOI: 10.1055/s-2006-941443. View

Su L, Wang D, Fan X . Comprehensive therapy for hemangioma presenting with Kasabach-Merritt syndrome in the maxillofacial region. J Oral Maxillofac Surg. 2014; 73(1):92-8. DOI: 10.1016/j.joms.2014.07.037. View

10.

Imafuku S, Hosokawa C, Moroi Y, Furue M . Kasabach-Merritt syndrome associated with angiosarcoma of the scalp successfully treated with chemoradiotherapy. Acta Derm Venereol. 2008; 88(2):193-4. DOI: 10.2340/00015555-0378. View

11.

Drolet B, Scott L, Esterly N, Gosain A . Early surgical intervention in a patient with Kasabach-Merritt phenomenon. J Pediatr. 2001; 138(5):756-8. DOI: 10.1067/mpd.2001.112650. View