High-intensity Focused Ultrasound Ablation: a Non-surgical Approach to Treat Advanced and Complicated Liver Alveococcosis

Overview

Journal J Med Ultrason (2001)

Specialty Radiology

Date 2018 Oct 25

PMID 30353443

Authors

Nurlan Zhampeissov

Erlan Manap

Kulsara Rustemova

Galina Fedotovskikh

Turlybek Tuganbekov

Suindyk Imankulov

Abduzhappar Gaipov

Affiliations

Soon will be listed here.

Abstract

Liver alveococcosis is a life-threatening parasitic disease with progressive growth and wide metastasis to neighboring tissues, lungs, and brain. The radical treatment option is surgery along with a few chemical therapies. However, the frequency of progression and recurrence, as well as postoperative complications and mortality, remains very high. The high-intensity focused ultrasound (HIFU) treatment system, a therapeutic application using ultrasound to deliver heat or agitation into the body, was initially designed to treat cancer. Advanced and complicated forms of liver alveococcosis usually require surgical treatment to provide partial ectomy of necrotized liver tissue along with alveococcal caverns and sanitation of the peritoneal cavity. In this article, we presented a case of successful HIFU ablation with transhepatic puncture and drainage in treatment of complicated and advanced liver alveococcosis to avoid wide surgical treatment.

References

Kern P, Bardonnet K, Renner E, Auer H, Pawlowski Z, Ammann R . European echinococcosis registry: human alveolar echinococcosis, Europe, 1982-2000. Emerg Infect Dis. 2003; 9(3):343-9. PMC: 2958541. DOI: 10.3201/eid0903.020341. View

Buttenschoen K, Gruener B, Carli Buttenschoen D, Reuter S, Henne-Bruns D, Kern P . Palliative operation for the treatment of alveolar echinococcosis. Langenbecks Arch Surg. 2008; 394(1):199-204. DOI: 10.1007/s00423-008-0367-6. View

Zou X, Wang J, Zhao H, Zhang J, Wu W, Ye B . Echinococcus granulosus: protoscolicidal effect of high intensity focused ultrasound. Exp Parasitol. 2008; 121(4):312-6. DOI: 10.1016/j.exppara.2008.12.002. View

Brunetti E, Kern P, Vuitton D . Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop. 2009; 114(1):1-16. DOI: 10.1016/j.actatropica.2009.11.001. View

Kawamura N, Kamiyama T, Sato N, Nakanishi K, Yokoo H, Kamachi H . Long-term results of hepatectomy for patients with alveolar echinococcosis: a single-center experience. J Am Coll Surg. 2011; 212(5):804-12. DOI: 10.1016/j.jamcollsurg.2011.02.007. View

Cai H, Chen L, Ye B, Liu A, Zhang J, Zhao Y . The destructive effects of high-intensity focused ultrasound on hydatid cysts enhanced by ultrasound contrast agent and superabsorbent polymer alone or in combination. Parasitol Res. 2012; 112(2):707-17. DOI: 10.1007/s00436-012-3191-4. View

Tamarozzi F, Vuitton L, Brunetti E, Vuitton D, Koch S . Non-surgical and non-chemical attempts to treat echinococcosis: do they work?. Parasite. 2014; 21:75. PMC: 4273701. DOI: 10.1051/parasite/2014071. View

Imankulov S, Fedotovskikh G, Shaimardanova G, Yerlan M, Zhampeisov N . Feasibility study of high intensity focused ultrasound (HIFU) for the treatment of hydatid cysts of the liver. Ultrason Sonochem. 2015; 27:712-716. DOI: 10.1016/j.ultsonch.2015.05.025. View

Imankulov S, Fedotovskikh G, Zhampeissov N, Yerlan M, Shaimardanova G, Knaub L . Treatment of liver alveococcosis with high-intensity focused ultrasound. Ultrason Sonochem. 2015; 27:707-711. DOI: 10.1016/j.ultsonch.2015.05.022. View

10.

Hsiao Y, Kuo S, Tsai H, Chou M, Yeh G . Clinical Application of High-intensity Focused Ultrasound in Cancer Therapy. J Cancer. 2016; 7(3):225-31. PMC: 4747875. DOI: 10.7150/jca.13906. View

11.

Patkowski W, Kotulski M, Remiszewski P, Grat M, Zieniewicz K, Kobryn K . Alveococcosis of the liver - strategy of surgical treatment with special focus on liver transplantation. Transpl Infect Dis. 2016; 18(5):661-666. DOI: 10.1111/tid.12574. View

12.

Shikhman S . [Analysis of mortality after surgery for alveococcosis of the liver]. Vestn Khir Im I I Grek. 1982; 129(7):32-7. View

13.

. Guidelines for treatment of cystic and alveolar echinococcosis in humans. WHO Informal Working Group on Echinococcosis. Bull World Health Organ. 1996; 74(3):231-42. PMC: 2486920. View

14.

Ishizu H, Uchino J, Sato N, Aoki S, Suzuki K, Kuribayashi H . Effect of albendazole on recurrent and residual alveolar echinococcosis of the liver after surgery. Hepatology. 1997; 25(3):528-31. DOI: 10.1002/hep.510250305. View

15.

Deplazes P, Eckert J . Diagnosis of the Echinococcus multilocularis infection in final hosts. Appl Parasitol. 1996; 37(4):245-52. View