Benefits and Consequences of Testosterone Replacement Therapy: A Review

Overview

Journal Eur Endocrinol

Specialty Endocrinology

Date 2018 Oct 24

PMID 30349612

Citations 3

Authors

Polackwich As

Tadros Nn

Ostrowski Ka

Hedges Jc

Affiliations

Soon will be listed here.

Abstract

Late onset hypogonadism (LOH) is an issue of increasing concern. Studies have shown the importance of testosterone in the maintenance of homeostasis, especially with respect to bone health, sexual function, diabetes, cardiovascular risk, mental health and cognition. Much of the dysfunction in hypogonadism can be reversed or improved with testosterone replacement therapy (TRT). Physicians worry about the possible consequences of TRT, especially regarding the prostate. By reviewing the literature, we have found there are significant benefits to TRT, and fears of adverse effects on the prostate are largely unfounded, though there is a great need for larger studies with longer periods of follow-up, especially to evaluate adverse events.

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