Antibiotic Resistance: a Rundown of a Global Crisis

Overview

Journal Infect Drug Resist

Publisher Dove Medical Press

Date 2018 Oct 24

PMID 30349322

Citations 776

Authors

Bilal Aslam

Wei Wang

Muhammad Imran Arshad

Mohsin Khurshid

Saima Muzammil

Muhammad Hidayat Rasool

Muhammad Atif Nisar

Ruman Farooq Alvi

Muhammad Aamir Aslam

Muhammad Usman Qamar

Muhammad Khalid Farooq Salamat

Zulqarnain Baloch

Affiliations

Soon will be listed here.

Abstract

The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial resistance has been ascribed to the misuse of these agents and due to unavailability of newer drugs attributable to exigent regulatory requirements and reduced financial inducements. Comprehensive efforts are needed to minimize the pace of resistance by studying emergent microorganisms, resistance mechanisms, and antimicrobial agents. Multidisciplinary approaches are required across health care settings as well as environment and agriculture sectors. Progressive alternate approaches including probiotics, antibodies, and vaccines have shown promising results in trials that suggest the role of these alternatives as preventive or adjunct therapies in future.

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