Identification of Leishmania Species in Naturally Infected Sand Flies from Refugee Camps, Greece

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2018 Oct 23

PMID 30346269

Citations 12

Authors

Emmanouil A Fotakis

Ioannis A Giantsis

Aimilia Avgerinou

Sofoklis Kourtidis

Evangelia Agathaggelidou

Christina Kapoula

Glykeria Dadakou

John Vontas

Alexandra Chaskopoulou

Affiliations

Soon will be listed here.

Abstract

High infection rates of Leishmania donovani and L. tropica were detected in Phlebotomus spp. sand flies collected from refugee camps in Greece, indicating increased risk of infection among local populations. Detection and treatment of leishmaniasis, community education, and vector control are essential measures to prevent pathogen transmission and protect public health.

Citing Articles

Leishmaniasis in Greece: Prospects of transitioning to a One Health surveillance system.

Fotakis E, Papamichail D, Boutsini S, Patsoula E, Panagiotopoulos T One Health. 2024; 19:100896.

PMID: 39350935 PMC: 11440306. DOI: 10.1016/j.onehlt.2024.100896.

The spatial relationship between leishmaniases and sand flies in Europe and neighboring countries.

Berriatua E, Perez-Cutillas P, Vidal A, Briet O Parasit Vectors. 2024; 17(1):404.

PMID: 39334428 PMC: 11437717. DOI: 10.1186/s13071-024-06484-2.

Evidence of Horse Exposure to , , and in Greece through the Detection of IgG Antibodies in Serum and in an Alternative Diagnostic Sample-The Saliva.

Athanasiou L, Katsogiannou E, Tyrnenopoulou P, Gougoulis D, Apostolidis K, Papadakis S Biomolecules. 2023; 13(9).

PMID: 37759774 PMC: 10526806. DOI: 10.3390/biom13091374.

Leishmaniosis in Greece: The Veterinary Perspective.

Symeonidou I, Sioutas G, Gelasakis A, Tsokana C, Papadopoulos E Pathogens. 2023; 12(6).

PMID: 37375459 PMC: 10303642. DOI: 10.3390/pathogens12060769.

Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021-A Comprehensive Review.

Rocha R, Pereira A, Maia C Pathogens. 2022; 11(8).

PMID: 36015042 PMC: 9415673. DOI: 10.3390/pathogens11080921.

References

Katholi C, Unnasch T . Important experimental parameters for determining infection rates in arthropod vectors using pool screening approaches. Am J Trop Med Hyg. 2006; 74(5):779-85. View

Van der Auwera G, Maes I, De Doncker S, Ravel C, Cnops L, Van Esbroeck M . Heat-shock protein 70 gene sequencing for Leishmania species typing in European tropical infectious disease clinics. Euro Surveill. 2013; 18(30):20543. DOI: 10.2807/1560-7917.es2013.18.30.20543. View

Schonian G, Nasereddin A, Dinse N, Schweynoch C, Schallig H, Presber W . PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagn Microbiol Infect Dis. 2003; 47(1):349-58. DOI: 10.1016/s0732-8893(03)00093-2. View

Giantsis I, Chaskopoulou A, Bon M . Direct Multiplex PCR (dmPCR) for the Identification of Six Phlebotomine Sand Fly Species (Diptera: Psychodidae), Including Major Leishmania Vectors of the Mediterranean. J Econ Entomol. 2016; 110(1):245-249. DOI: 10.1093/jee/tow269. View

Rego F, Rugani J, Shimabukuro P, Tonelli G, Quaresma P, Gontijo C . Molecular detection of Leishmania in phlebotomine sand flies (Diptera: Psychodidae) from a cutaneous leishmaniasis focus atXakriabá Indigenous Reserve, Brazil. PLoS One. 2015; 10(4):e0122038. PMC: 4390197. DOI: 10.1371/journal.pone.0122038. View

Ntais P, Sifaki-Pistola D, Christodoulou V, Messaritakis I, Pratlong F, Poupalos G . Leishmaniases in Greece. Am J Trop Med Hyg. 2013; 89(5):906-15. PMC: 3820334. DOI: 10.4269/ajtmh.13-0070. View

Saroufim M, Charafeddine K, Issa G, Khalifeh H, Habib R, Berry A . Ongoing epidemic of cutaneous leishmaniasis among Syrian refugees, Lebanon. Emerg Infect Dis. 2014; 20(10):1712-5. PMC: 4193275. DOI: 10.3201/eid2010.140288. View

Chaskopoulou A, Giantsis I, Demir S, Bon M . Species composition, activity patterns and blood meal analysis of sand fly populations (Diptera: Psychodidae) in the metropolitan region of Thessaloniki, an endemic focus of canine leishmaniasis. Acta Trop. 2016; 158:170-176. DOI: 10.1016/j.actatropica.2016.03.006. View

Hadighi R, Mohebali M, Boucher P, Hajjaran H, Khamesipour A, Ouellette M . Unresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites. PLoS Med. 2006; 3(5):e162. PMC: 1435779. DOI: 10.1371/journal.pmed.0030162. View

10.

Hide M, Banuls A . Species-specific PCR assay for L. infantum/L. donovani discrimination. Acta Trop. 2006; 100(3):241-5. DOI: 10.1016/j.actatropica.2006.10.012. View

11.

Tamura K, Stecher G, Peterson D, Filipski A, Kumar S . MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013; 30(12):2725-9. PMC: 3840312. DOI: 10.1093/molbev/mst197. View

12.

Dujardin J, Campino L, Canavate C, Dedet J, Gradoni L, Soteriadou K . Spread of vector-borne diseases and neglect of Leishmaniasis, Europe. Emerg Infect Dis. 2008; 14(7):1013-8. PMC: 2600355. DOI: 10.3201/eid1407.071589. View