The Antioxidant Compounds Isolated from the Fruits of Chinese Wild Raspberry Hu

Raspberry, the fruit of Hu, is a widely distributed economic staple food in China. It has long been used as a traditional medicine in mainland China to treat kidney enuresis, nocturnal emission and premature ejaculation in clinic. In this paper, six known compounds (-) were purified from the fruits of . Their structures were elucidated as (16α)-16,17-dihydroxy--kauran-2-one17-O--D-glucopyranoside (), (16) -16,17-dihydroxy--kaurane-2-one (), 3,3'-di-O-methylellagic acid 4-(5''-acetyl)--L-arabinofuranoside (), quercilicoside A (), esculetine () and ethyl--D-glucoside (). All the compounds were isolated from Hu for the first time. Compounds and shown distinctive free radical scavenging activities in DPPH and FRAP assays. In addition, no cytotoxicity was observed for compounds and against different cancer cells, suggesting that they might be useful as potential antioxidant agents against various reactive oxygen species.[Formula: see text].