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Prevalence of Inflammatory Back Pain and Radiologic Sacroiliitis is Increased in Patients with Primary Sjögren's Syndrome

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Journal Pan Afr Med J
Date 2018 Oct 23
PMID 30344882
Citations 4
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Abstract

Introduction: The prevalence of Sjögren's syndrome (SS) in patients with the diagnosis of SpA has been reported to be higher than normal population. Yet, the vice-versa is unclear. In this study, we aimed to investigate the prevalence of IBP, radiologic sacroiliitis and SpA in patients with primary SS.

Methods: 85 patients followed at the rheumatology clinics of the Marmara and Kocaeli Universities with the diagnosis of primary SS between November 2011 and August 2012 were included in this study. The control group consisted of 100 age-and gender-matched patients. Inflammatory back pain and axial SpA were diagnosed according to the assessment of spondylo arthritis International Society (ASAS) criteria.

Results: 83 patients were (97%) female and 2 (3%) were male. Mean age of the patients was 49.1 (±11) years. Mean disease duration was 7.3 (±4) years. The patient and control groups were comparable in terms of age and gender (p > 0.05). Inflammatory back pain was observed in 21 (24.7%) of 85 primary SS patients and in 4 (4%) of 100 control subjects (p < 0.001), radiographic sacroiliitis was demonstrated in 9 (10.5%) of primary SS patients and 2 (2%) of the control subjects (p = 0.025). Remaining SpA findings were not encountered in either group.

Conclusion: inflammatory back pain and radiologic sacroiliitis is increased in patients with primary SS. Whether IBP, SI joint inflammation and radiologic sacroiliitis is due to the co-existence of SpA and primary SS or IBP is an underdiagnosed clinical feature of SS deserves further studies of large patient numbers.

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References
1.
Ramos-Casals M, Tzioufas A, Font J . Primary Sjögren's syndrome: new clinical and therapeutic concepts. Ann Rheum Dis. 2004; 64(3):347-54. PMC: 1755414. DOI: 10.1136/ard.2004.025676. View

2.
Rudwaleit M, van der Heijde D, Landewe R, Listing J, Akkoc N, Brandt J . The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009; 68(6):777-83. DOI: 10.1136/ard.2009.108233. View

3.
Scotto Di Fazano C, Vergne P, Coyral D, Inaoui R, Bonnet C, Bertin P . Is the relationship between spondyloarthropathy and Sjögren's syndrome in women coincidental? A study of 13 cases. Joint Bone Spine. 2002; 69(4):383-7. DOI: 10.1016/s1297-319x(02)00414-1. View

4.
Klauser A, Bollow M, Calin A, Frauscher F, Kainberger F, Moncayo R . Workshop report: clinical diagnosis and imaging of sacroiliitis, Innsbruck, Austria, October 9, 2003. J Rheumatol. 2004; 31(10):2041-7. View

5.
Canella C, Schau B, Ribeiro E, Sbaffi B, Marchiori E . MRI in seronegative spondyloarthritis: imaging features and differential diagnosis in the spine and sacroiliac joints. AJR Am J Roentgenol. 2012; 200(1):149-57. DOI: 10.2214/AJR.12.8858. View