Effects of PH on Protein Binding of Lidocaine

Overview

Journal Anesth Analg

Specialty Anesthesiology

Date 1978 Jul 1

PMID 30342

Citations 13

Authors

R G BURNEY

C A Difazio

J A Foster

Affiliations

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Abstract

Protein binding of lidocaine (2.5, 5, 10, and 20 microgram/ml in fresh plasma was studied from pH 5.6 to pH 9.8. Percent binding of lidocaine was inversely related to hydrogen-ion and lidocaine concentrations.

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