Duration and Time Trends in Hospital Stay for Very Preterm Infants Differ Across European Regions

Overview

Journal Pediatr Crit Care Med

Specialty Pediatrics

Date 2018 Oct 19

PMID 30334907

Citations 15

Authors

Rolf F Maier

Beatrice Blondel

Aurelie Piedvache

Bjoern Misselwitz

Stavros Petrou

Patrick Van Reempts

Francesco Franco

Henrique Barros

Janusz Gadzinowski

Klaus Boerch

Arno van Heijst

Elizabeth S Draper

Jennifer Zeitlin

Affiliations

Soon will be listed here.

Abstract

Objectives: To compare duration and changes over time in length of hospital stay for very preterm and extremely preterm infants in 10 European regions.

Design: Two area-based cohort studies from the same regions in 2003 and 2011/2012.

Setting: Ten regions from nine European countries.

Patients: Infants born between 22 + 0 and 31 + 6 weeks of gestational age and surviving to discharge (Models of Organising Access to Intensive Care for Very Preterm Births cohort in 2003, n = 4,011 and Effective Perinatal Intensive Care in Europe cohort in 2011/2012, n = 4,336).

Interventions: Observational study, no intervention.

Measurements And Main Results: Maternal and infant characteristics were abstracted from medical records using a common protocol and length of stay until discharge was adjusted for case-mix using negative binomial regression. Mean length of stay was 63.6 days in 2003 and varied from 52.4 to 76.5 days across regions. In 2011/2012, mean length of stay was 63.1 days, with a narrower regional range (54.0-70.1). Low gestational age, small for gestational age, low 5-minute Apgar score, surfactant administration, any surgery, and severe neonatal morbidities increased length of stay. Infant characteristics explained some of the differences between regions and over time, but large variations remained after adjustment. In 2011/2012, mean adjusted length of stay ranged from less than 54 days in the Northern region of the United Kingdom and Wielkopolska, Poland to over 67 days in the Ile-de-France region of France and the Eastern region of the Netherlands. No systematic decrease in very preterm length of stay was observed over time after adjustment for patient case-mix.

Conclusions: A better understanding of the discharge criteria and care practices that contribute to the wide differences in very preterm length of stay across European regions could inform policies to optimize discharge decisions in terms of infant outcomes and health system costs.

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Sexty R, van der Pal S, Reijneveld S, Wolke D, Luchters G, Bakker L BMC Pediatr. 2023; 23(1):554.

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