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Hypersensitivity to Metallic Implants: Pathophysiologic and Diagnostic Considerations

Overview
Journal Acta Biomed
Specialty General Medicine
Date 2018 Oct 19
PMID 30333472
Citations 1
Authors
Nicholas G Kounis
Ioanna Koniari
Affiliations
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Abstract

Metals are ubiquitous in the surrounding environment and constitute an important class of substances that can act as allergens. Consumer products such as earings, zip, jewellery, cosmetics, paints, dental and body implants as well as endovascular, intracardiac and orthopedic devices are made from metals. Metal anions eluted from various metals  are common allergic sensitizers. In Europe nickel, chromium and cobalt induce allergic skin reactions in about 20%, 4%, and 7% while in the United States14%, 4%, and 9% respectively.

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Chen A, Kurmis A Arthroplasty. 2024; 6(1):1.

PMID: 38303027 PMC: 10835847. DOI: 10.1186/s42836-023-00227-x.

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