Lean Body Mass in the Prediction of Bone Mineral Density in Postmenopausal Women

Overview

Journal Biores Open Access

Publisher Mary Ann Liebert

Specialty Biology

Date 2018 Oct 18

PMID 30327744

Citations 22

Authors

Bolaji Lilian Ilesanmi-Oyelere

Jane Coad

Nicole Roy

Marlena Cathorina Kruger

Affiliations

Soon will be listed here.

Abstract

Owing to conflicting results of the association between body composition and bone mineral density (BMD), we investigated the relationship between fat mass (FM), lean mass (LM), and BMD in New Zealand postmenopausal women. We hypothesized that increased LM will indicate a higher BMD. A cross-sectional study was performed examining the associations between body composition, anthropometric measures, activity energy expenditure, and bone health status (using dual-energy X-ray absorptiometry [DXA]). A total of 127 healthy postmenopausal women aged between 54 and 81 years. Both FM and LM were significantly associated with BMD at all sites. However, LM, not FM, was the strongest predictor of femoral neck (FN) BMD (β = 0.497, < 0.001), hip BMD (β = 0.495, < 0.001), spine BMD (β = 0.449, < 0.001), and whole body BMD (β = 0.406, < 0.001). Age was negatively associated with FN and hip BMD. LM was positively associated with FN, spine, hip, and whole body BMD. Our findings suggest the need to increase LM rather than FM highlighting the importance of physical activity for this age group.

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