Granular Cell Tumor of the Ascending Colon: a Case Report
Overview
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A granular cell tumor (granular cell myoblastoma) of the ascending colon in a 48-year old male is reported. The tumor was detected by barium enema study as a sessile polyp, and colonofiberscopy revealed submucosal tumor. It was removed by endoscopic polypectomy. Macroscopic examination showed the characteristic features of granular cell tumor. The avidin-biotin-peroxidase complex (ABC) method for detection of S-100 protein demonstrated that the cytoplasm of tumor cells and the pleomorphic nuclei were strongly stained with anti-S-100 protein serum, which supports the concept of the Schwann cell origin of granular cell tumor.
Granular cell tumors: a report of six cases.
Aoyama K, Kamio T, Hirano A, Seshimo A, Kameoka S World J Surg Oncol. 2012; 10:204.
PMID: 23021251 PMC: 3502223. DOI: 10.1186/1477-7819-10-204.