» Articles » PMID: 30319935

Psychosocial Treatment of Irritability in Youth

Overview
Specialty Psychiatry
Date 2018 Oct 16
PMID 30319935
Citations 25
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose Of Review: Chronic, severe irritability is a common presenting problem in children and adolescents. Disruptive mood dysregulation disorder (DMDD) was added to the DSM-5 in recognition of this public health need. Currently there are no well-established, evidence-based pharmacological or psychosocial treatments specifically for DMDD. Here, we focus on psychosocial interventions. In addition to reviewing published research, we present preliminary, open trial data on a novel exposure-based cognitive-behavioral therapy (CBT) targeting severe irritability, as is present in DMDD.

Recent Findings: In the published literature, parent management training (PMT) comprises parent-based interventions designed to treat youth disruptive behavior. Child-based interventions for disruptive behavior include CBT focused on social cognition and problem-solving. Based on identified treatment gaps for severe irritability in children and adolescents, novel psychosocial interventions are being developed. We have developed a CBT for severe irritability that integrates exposure techniques, drawn from anxiety treatment, with selected PMT techniques. Data from an open pilot trial (=10) suggest feasibility.

Summary: Promising psychosocial treatments are being developed for DMDD. Future directions include testing these new therapies against extant interventions. Increased research on the biological and psychological mechanisms mediating irritability will further bridge the treatment gap for youth and families.

Citing Articles

Treatment adherence, therapeutic alliance, and clinical outcomes during an exposure-based cognitive-behavioral therapy for pediatric irritability.

Naim R, German R, White J, Pandya U, Dombek K, Clayton M BMC Psychiatry. 2025; 25(1):181.

PMID: 40012036 PMC: 11866884. DOI: 10.1186/s12888-025-06601-0.


Substance-involved child-to-parent violence.

Harries T, Mayshak R, Skvarc D, Eckhardt C, Benstead M, Miller P Drug Alcohol Rev. 2025; 44(3):820-828.

PMID: 39894469 PMC: 11886503. DOI: 10.1111/dar.14011.


Phasic Versus Tonic Irritability and Associations with Family Accommodation Among Youth with Selective Mutism: A Latent Profile Analysis.

Freitag G, Coxe S, Cardinale E, Furr J, Herrera A, Comer J Res Child Adolesc Psychopathol. 2024; 52(6):905-917.

PMID: 38270833 DOI: 10.1007/s10802-023-01161-x.


A Delphi consensus among experts on assessment and treatment of disruptive mood dysregulation disorder.

Boudjerida A, Guile J, Breton J, Benarous X, Cohen D, Labelle R Front Psychiatry. 2024; 14:1166228.

PMID: 38260796 PMC: 10800807. DOI: 10.3389/fpsyt.2023.1166228.


A network approach to the investigation of childhood irritability: probing frustration using social stimuli.

Thompson K, Schneider C, Lopez-Roque J, Wakschlag L, Karim H, Perlman S J Child Psychol Psychiatry. 2023; 65(7):959-972.

PMID: 38124618 PMC: 11161318. DOI: 10.1111/jcpp.13937.


References
1.
Stringaris A, Cohen P, Pine D, Leibenluft E . Adult outcomes of youth irritability: a 20-year prospective community-based study. Am J Psychiatry. 2009; 166(9):1048-54. PMC: 2791884. DOI: 10.1176/appi.ajp.2009.08121849. View

2.
Stringaris A, Vidal-Ribas P, Brotman M, Leibenluft E . Practitioner Review: Definition, recognition, and treatment challenges of irritability in young people. J Child Psychol Psychiatry. 2017; 59(7):721-739. DOI: 10.1111/jcpp.12823. View

3.
Wakschlag L, Choi S, Carter A, Hullsiek H, Burns J, McCarthy K . Defining the developmental parameters of temper loss in early childhood: implications for developmental psychopathology. J Child Psychol Psychiatry. 2012; 53(11):1099-108. PMC: 3633202. DOI: 10.1111/j.1469-7610.2012.02595.x. View

4.
Brotman M, Kircanski K, Leibenluft E . Irritability in Children and Adolescents. Annu Rev Clin Psychol. 2017; 13:317-341. DOI: 10.1146/annurev-clinpsy-032816-044941. View

5.
Conner K, Meldrum S, Wieczorek W, Duberstein P, Welte J . The association of irritability and impulsivity with suicidal ideation among 15- to 20-year-old males. Suicide Life Threat Behav. 2004; 34(4):363-73. DOI: 10.1521/suli.34.4.363.53745. View