Calcium-activated Protease in Hamster Cardiomyopathy

Overview

Journal Muscle Nerve

Date 1987 Jan 1

PMID 3031497

Citations 2

Authors

M Spalla

T H Kuo

J Wiener

Affiliations

Soon will be listed here.

Abstract

A high calcium-requiring protease was purified from the hearts of myopathic hamsters. The biochemical properties of the enzyme were studied with [3H]acetylcasein as substrate. Comparison of the enzyme from hamster and rat hearts indicated no species specificity. Increased levels of the enzyme were associated with the development of cardiac lesions in myopathic hamsters.

Citing Articles

Altered Ca2+ homeostasis and impaired mitochondrial function in cardiomyopathy.

Kuo T, Zhu L, Golden K, Marsh J, Bhattacharya S Mol Cell Biochem. 2002; 238(1-2):119-27.

PMID: 12349899 DOI: 10.1023/a:1019967323419.

Affinity labelling of the Ca(2+)-activated neutral proteinase (calpain) in intact human platelets.

Anagli J, Hagmann J, Shaw E Biochem J. 1993; 289 ( Pt 1):93-9.

PMID: 8424777 PMC: 1132135. DOI: 10.1042/bj2890093.