Patients with Primary Membranous Nephropathy Lack Auto-antibodies Against LDL Receptor, the Homologue of Megalin in Human Glomeruli

Overview

Journal Clin Kidney J

Publisher Oxford University Press

Specialty Nephrology

Date 2018 Oct 12

PMID 30305893

Citations 3

Authors

Maurizio Bruschi

Giovanni Candiano

Corrado Murtas

Marco Prunotto

Laura Santucci

Maria Luisa Carnevali

Francesco Scolari

Landino Allegri

Gian Marco Ghiggeri

Affiliations

Soon will be listed here.

Citing Articles

Immunology of membranous nephropathy: from animal models to humans.

Sinico R, Mezzina N, Trezzi B, Ghiggeri G, Radice A Clin Exp Immunol. 2015; 183(2):157-65.

PMID: 26459770 PMC: 4711165. DOI: 10.1111/cei.12729.

Identification and characterization of a new autoimmune protein in membranous nephropathy by immunoscreening of a renal cDNA library.

Cavazzini F, Magistroni R, Furci L, Lupo V, Ligabue G, Granito M PLoS One. 2012; 7(11):e48845.

PMID: 23144993 PMC: 3493607. DOI: 10.1371/journal.pone.0048845.

Autoimmunity in membranous nephropathy targets aldose reductase and SOD2.

Prunotto M, Carnevali M, Candiano G, Murtas C, Bruschi M, Corradini E J Am Soc Nephrol. 2010; 21(3):507-19.

PMID: 20150532 PMC: 2831859. DOI: 10.1681/ASN.2008121259.

References

Kerjaschki D, Horvat R, Binder S, Susani M, Dekan G, Ojha P . Identification of a 400-kd protein in the brush borders of human kidney tubules that is similar to gp330, the nephritogenic antigen of rat Heymann nephritis. Am J Pathol. 1987; 129(1):183-91. PMC: 1899684. View

HEYMANN W, HACKEL D, Harwood S, Wilson S, HUNTER J . Production of nephrotic syndrome in rats by Freund's adjuvants and rat kidney suspensions. Proc Soc Exp Biol Med. 1959; 100(4):660-4. DOI: 10.3181/00379727-100-24736. View

Collins A, Andres G, McCluskey R . Lack of evidence for a role of renal tubular antigen in human membranous glomerulonephritis. Nephron. 1981; 27(6):297-301. DOI: 10.1159/000182074. View

Debiec H, Guigonis V, Mougenot B, Decobert F, Haymann J, Bensman A . Antenatal membranous glomerulonephritis due to anti-neutral endopeptidase antibodies. N Engl J Med. 2002; 346(26):2053-60. DOI: 10.1056/NEJMoa012895. View

Rastaldi M, Candiano G, Musante L, Bruschi M, Armelloni S, Rimoldi L . Glomerular clusterin is associated with PKC-alpha/beta regulation and good outcome of membranous glomerulonephritis in humans. Kidney Int. 2006; 70(3):477-85. DOI: 10.1038/sj.ki.5001563. View