Changing Patterns of Adult Asthma Incidence: Results from the National Health Insurance Service-National Sample Cohort (NHIS-NSC) Database in Korea

Overview

Journal Sci Rep

Specialty Science

Date 2018 Oct 11

PMID 30302007

Citations 16

Authors

Ji-Yeon Shin

Kyoung-Hee Sohn

Ji Eun Shin

Mira Park

Jiseun Lim

Jin Yong Lee

Min-Suk Yang

Affiliations

Soon will be listed here.

Abstract

This study was conducted to assess the changes in the annual incidence of adult asthma in Korea where the prevalence of asthma had increased steadily in recent decades. A population-based cohort study was conducted using the National Health Insurance Service-National Sample Cohort (NHIS-NSC), which consisted of 746,816 adults aged >20 years between 2004 and 2012. Asthma was defined by two or more physician claims on the basis of a primary diagnostic code for asthma and administration of asthma medications within 1 year. The incidence rates and annual percent change were calculated, and the influence of age and sex on the incidence rates was studied. The annual asthma incidence increased from 3.63 in 2004 to 6.07 per 1,000 person-years in 2008. Since 2008, the asthma incidence did not change significantly. The asthma incidence was higher in women than in men throughout the study periods (p < 0.001) and higher in older than younger age groups (p < 0.001). The asthma incidence did not change in all ages since 2008, except for the 20 s who showed a steady increase. The incidence of asthma in adults reached plateau in Korea, which is consistent with the results from studies in other countries.

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References

Edwards B, Noone A, Mariotto A, Simard E, Boscoe F, Henley S . Annual Report to the Nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. Cancer. 2013; 120(9):1290-314. PMC: 3999205. DOI: 10.1002/cncr.28509. View

Kwon J, Kim B, Song Y, Seo J, Kim T, Yu J . Changes in the prevalence of childhood asthma in seoul from 1995 to 2008 and its risk factors. Allergy Asthma Immunol Res. 2011; 3(1):27-33. PMC: 3005315. DOI: 10.4168/aair.2011.3.1.27. View

Kim C, Park H, Ko S, Chang S, Moon H, Kim Y . The financial burden of asthma: a nationwide comprehensive survey conducted in the republic of Korea. Allergy Asthma Immunol Res. 2011; 3(1):34-8. PMC: 3005317. DOI: 10.4168/aair.2011.3.1.34. View

Engelkes M, Janssens H, de Ridder M, de Jongste J, Sturkenboom M, Verhamme K . Time trends in the incidence, prevalence and age at diagnosis of asthma in children. Pediatr Allergy Immunol. 2015; 26(4):367-74. DOI: 10.1111/pai.12376. View

Song W, Kang M, Chang Y, Cho S . Epidemiology of adult asthma in Asia: toward a better understanding. Asia Pac Allergy. 2014; 4(2):75-85. PMC: 4005350. DOI: 10.5415/apallergy.2014.4.2.75. View

Mukherjee M, Stoddart A, Gupta R, Nwaru B, Farr A, Heaven M . The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases. BMC Med. 2016; 14(1):113. PMC: 5002970. DOI: 10.1186/s12916-016-0657-8. View

Eder W, Ege M, von Mutius E . The asthma epidemic. N Engl J Med. 2006; 355(21):2226-35. DOI: 10.1056/NEJMra054308. View

Pearce N, Douwes J . Commentary: asthma time trends--mission accomplished?. Int J Epidemiol. 2005; 34(5):1018-9. DOI: 10.1093/ije/dyi115. View

Gershon A, Guan J, Wang C, To T . Trends in asthma prevalence and incidence in Ontario, Canada, 1996-2005: a population study. Am J Epidemiol. 2010; 172(6):728-36. DOI: 10.1093/aje/kwq189. View

10.

Simpson C, Sheikh A . Trends in the epidemiology of asthma in England: a national study of 333,294 patients. J R Soc Med. 2010; 103(3):98-106. PMC: 3072257. DOI: 10.1258/jrsm.2009.090348. View

11.

Kim B, Kim J, Kang M, Yang M, Park H, Min K . Allergies are still on the rise? A 6-year nationwide population-based study in Korea. Allergol Int. 2015; 65(2):186-191. DOI: 10.1016/j.alit.2015.11.002. View

12.

Kim Y, Tak Y, Jee Y, Lee B, Kim S, Park H . High prevalence of current asthma and active smoking effect among the elderly. Clin Exp Allergy. 2003; 32(12):1706-12. DOI: 10.1046/j.1365-2222.2002.01524.x. View

13.

Eagan T, Brogger J, Eide G, Bakke P . The incidence of adult asthma: a review. Int J Tuberc Lung Dis. 2005; 9(6):603-12. View

14.

. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Respir Med. 2017; 5(9):691-706. PMC: 5573769. DOI: 10.1016/S2213-2600(17)30293-X. View

15.

Gibson G, Loddenkemper R, Lundback B, Sibille Y . Respiratory health and disease in Europe: the new European Lung White Book. Eur Respir J. 2013; 42(3):559-63. DOI: 10.1183/09031936.00105513. View

16.

Lee T, Kim J, Kim S, Kim K, Park Y, Kim Y . Risk factors for asthma-related healthcare use: longitudinal analysis using the NHI claims database in a Korean asthma cohort. PLoS One. 2014; 9(11):e112844. PMC: 4232512. DOI: 10.1371/journal.pone.0112844. View

17.

Purdy S, Griffin T, Salisbury C, Sharp D . Ambulatory care sensitive conditions: terminology and disease coding need to be more specific to aid policy makers and clinicians. Public Health. 2009; 123(2):169-73. DOI: 10.1016/j.puhe.2008.11.001. View

18.

. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet. 1998; 351(9111):1225-32. View

19.

Park C, Kang H, Kwon I, Kang D, Jung H . [Cost-of-illness study of asthma in Korea: estimated from the Korea National Health insurance claims database]. J Prev Med Public Health. 2006; 39(5):397-403. View

20.

Lee S . Prevalence of childhood asthma in Korea: international study of asthma and allergies in childhood. Allergy Asthma Immunol Res. 2010; 2(2):61-4. PMC: 2846742. DOI: 10.4168/aair.2010.2.2.61. View