Serum Uric Acid Levels in Type 2 Diabetes Mellitus: Is There a Linear Relationship with Severity of Carotid Atherosclerosis?

Overview

Journal Indian J Endocrinol Metab

Specialty Endocrinology

Date 2018 Oct 9

PMID 30294580

Authors

Shantan Venishetty

Rama Bhat

K V Rajagopal

Affiliations

Soon will be listed here.

Abstract

Aims: The aim of this study was to correlate serum uric acid (SUA) levels and carotid intima-media thickness (CIMT) in patients with type 2 diabetes mellitus (DM).

Settings And Design: This study was a cross-sectional observational study on 103 diabetic patients conducted from September 2015 to May 2017.

Subjects And Methods: We screened 103 patients with type 2 DM between the ages of 30-65 years. SUA levels and the CIMT were measured. The patients were divided into quartiles based on uric acid level. The CIMT of the quartiles is compared and analyzed.

Statistical Analysis Used: Chi-squared test, Analysis of Variance, and Pearson's correlation.

Results: Uric acid levels were positively associated with CIMT ( = 0.001). The association remained significant after further adjustment for potential confounders. Strong correlation was found among them as depicted by correlation coefficient (r = 0.779).

Conclusions: Carotid atherosclerosis as measured by IMT is associated with SUA levels in patients with type 2 DM.

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