» Articles » PMID: 30292779

Views of the Importance of Psychiatric Genetic Research by Potential Volunteers from Stakeholder Groups

Overview
Journal J Psychiatr Res
Specialty Psychiatry
Date 2018 Oct 8
PMID 30292779
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Few studies have explored potential volunteers' attitudes toward genetic research. To address this gap in the literature, we developed an empirical project to document views held by individuals who may wish to enroll in genetic studies involving mental disorders. People living with mental illness, family members of people with mental illness, and community comparison volunteers were queried regarding their views on the importance of genetic research generally, in comparison with medical research, and in relation to 12 health conditions categorized in four types. T-tests and univariate and multivariate analysis of variance were used as appropriate. Participants expressed support for the importance of genetic research (mean = 9.43, scale = 1-10) and endorsed genetic research more highly compared with non-genetic medical research (mean = 9.43 vs. 8.69, P value = <0.001). The most highly endorsed genetic research was for cognitive disorders, followed by mental illness disorders, physical illness disorders, and addiction disorders (means = 8.88, 8.26, 8.16 and 7.55, respectively, P value = <0.001). Overall, this study provides evidence of strong endorsement of genetic research over non-genetic research by potential volunteers.

Citing Articles

Perceived protectiveness of research safeguards and influences on willingness to participate in research: A novel MTurk pilot study.

Kim J, Ryan K, Tsungmey T, Kasun M, Roberts W, Dunn L J Psychiatr Res. 2021; 138:200-206.

PMID: 33865169 PMC: 8513533. DOI: 10.1016/j.jpsychires.2021.04.005.


Attitudes toward the right to autonomous decision-making in psychiatric genetic testing: Controversial and context-dependent.

Strohmaier J, Witt S, Frank J, Lemme N, Flatau L, Streit F Am J Med Genet B Neuropsychiatr Genet. 2019; 180(8):555-565.

PMID: 30912305 PMC: 6899643. DOI: 10.1002/ajmg.b.32724.


Perspectives of psychiatric investigators and IRB chairs regarding benefits of psychiatric genetics research.

Roberts L, Dunn L, Kim J, Rostami M J Psychiatr Res. 2018; 106:54-60.

PMID: 30273801 PMC: 6428055. DOI: 10.1016/j.jpsychires.2018.08.027.

References
1.
Schoneveld E, Lichtwarck-Aschoff A, Granic I . Preventing Childhood Anxiety Disorders: Is an Applied Game as Effective as a Cognitive Behavioral Therapy-Based Program?. Prev Sci. 2017; 19(2):220-232. PMC: 5801383. DOI: 10.1007/s11121-017-0843-8. View

2.
Roberts L, Kim J . Receptiveness to participation in genetic research: A pilot study comparing views of people with depression, diabetes, or no illness. J Psychiatr Res. 2017; 94:156-162. PMC: 5621512. DOI: 10.1016/j.jpsychires.2017.07.002. View

3.
Murphy E, Wickramaratne P, Weissman M . Racial and ethnic differences in willingness to participate in psychiatric genetic research. Psychiatr Genet. 2009; 19(4):186-94. PMC: 2742945. DOI: 10.1097/ypg.0b013e32832cec89. View

4.
Saraceno B, van Ommeren M, Batniji R, Cohen A, Gureje O, Mahoney J . Barriers to improvement of mental health services in low-income and middle-income countries. Lancet. 2007; 370(9593):1164-74. DOI: 10.1016/S0140-6736(07)61263-X. View

5.
Laegsgaard M, Mors O . Psychiatric genetic testing: attitudes and intentions among future users and providers. Am J Med Genet B Neuropsychiatr Genet. 2007; 147(3):375-84. DOI: 10.1002/ajmg.b.30609. View