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The Metabolomic Quest for a Biomarker in Chronic Kidney Disease

Overview
Journal Clin Kidney J
Specialty Nephrology
Date 2018 Oct 6
PMID 30288265
Citations 21
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Abstract

Chronic kidney disease (CKD) is a growing burden on people and on healthcare for which the diagnostics are niether disease-specific nor indicative of progression. Biomarkers are sought to enable clinicians to offer more appropriate patient-centred treatments, which could come to fruition by using a metabolomics approach. This mini-review highlights the current literature of metabolomics and CKD, and suggests additional factors that need to be considered in this quest for a biomarker, namely the diet and the gut microbiome, for more meaningful advances to be made.

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