ROK Study-C (Rainbow of KIBOU Study-colorectum): a Colorectal Cancer Survivor Cohort Study on Food, Nutrition, Physical Activity, Psychosocial Factors and Its Influences on Colorectal Cancer Recurrence, Survival and Quality of Life in Japan

Overview

Journal BMC Cancer

Publisher Biomed Central

Specialty Oncology

Date 2018 Oct 6

PMID 30286723

Citations 1

Authors

Yuri Mizota

Yukihide Kanemitsu

Shunsuke Tsukamoto

Dai Shida

Hiroki Ochiai

Seiichiro Yamamoto

Affiliations

Soon will be listed here.

Abstract

Background: Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer prognosis. To investigate the influence of lifestyle factors and psychosocial factors on prognosis, we started a prospective study of women with breast cancer, the Rainbow of KIBOU study-Breast (ROK Study-B) in 2007. As of February 2018, more than 6300 women have been enrolled, thus making this one of the world's largest cancer patient cohort studies. Based on the know-how obtained from this study, we started another new cohort study for colorectal cancer patient (ROK Study-C).

Methods: The ROK Study-C is a prospective observational study for colorectal cancer survivors at the National Cancer Center Hospital. Participants fill in several self-administrated questionnaires about lifestyle, psychosocial factors (including posttraumatic growth and benefit finding, support), and quality of life (QOL) 5 times in total: at diagnosis, 3 and 6 months, 1 and 5 years after surgery. CT-scans will be collected to assess body composition and obesity. We also use blood and cancer tissue from the Biobank. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related QOL. The planned sample size is 2000 and the follow-up period is 5 years after the last enrollment.

Discussion: Recruitment began in December 2015 and the study is still ongoing. The ROK Study-C will contribute to improvements in patient prognosis and yield important evidence for colorectal cancer survivorship.

Citing Articles

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References

Shea-Budgell M, Kostaras X, Myhill K, Hagen N . Information needs and sources of information for patients during cancer follow-up. Curr Oncol. 2014; 21(4):165-73. PMC: 4117614. DOI: 10.3747/co.21.1932. View

Finney Rutten L, Arora N, Bakos A, Aziz N, Rowland J . Information needs and sources of information among cancer patients: a systematic review of research (1980-2003). Patient Educ Couns. 2005; 57(3):250-61. DOI: 10.1016/j.pec.2004.06.006. View

Sawada T, Nishiyama T, Kikuchi N, Wang C, Lin Y, Mori M . The influence of personality and perceived stress on the development of breast cancer: 20-year follow-up of 29,098 Japanese women. Sci Rep. 2016; 6:32559. PMC: 5009304. DOI: 10.1038/srep32559. View

Aaronson N, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez N . The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993; 85(5):365-76. DOI: 10.1093/jnci/85.5.365. View

Herth K . The relationship between level of hope and level of coping response and other variables in patients with cancer. Oncol Nurs Forum. 1989; 16(1):67-72. View

Sasaki S, Kobayashi M, Tsugane S . Validity of a self-administered food frequency questionnaire used in the 5-year follow-up survey of the JPHC Study Cohort I: comparison with dietary records for food groups. J Epidemiol. 2003; 13(1 Suppl):S57-63. PMC: 9767694. DOI: 10.2188/jea.13.1sup_57. View

Takahashi M, Inokuchi T, Watanabe C, Saito T, Kai I . The Female Sexual Function Index (FSFI): development of a Japanese version. J Sex Med. 2011; 8(8):2246-54. DOI: 10.1111/j.1743-6109.2011.02267.x. View

Barry M, Fowler Jr F, OLeary M, Bruskewitz R, HOLTGREWE H, MEBUST W . The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol. 1992; 148(5):1549-57; discussion 1564. DOI: 10.1016/s0022-5347(17)36966-5. View

Nissen N, Lunde A, Pedersen C, Johannessen H . The use of complementary and alternative medicine after the completion of hospital treatment for colorectal cancer: findings from a questionnaire study in Denmark. BMC Complement Altern Med. 2014; 14:388. PMC: 4197266. DOI: 10.1186/1472-6882-14-388. View

10.

Sasaki S, Ishihara J, Tsugane S . Reproducibility of a self-administered food frequency questionnaire used in the 5-year follow-up survey of the JPHC Study Cohort I to assess food and nutrient intake. J Epidemiol. 2003; 13(1 Suppl):S115-24. PMC: 9767696. DOI: 10.2188/jea.13.1sup_115. View

11.

Sasaki S, Kobayashi M, Ishihara J, Tsugane S . Self-administered food frequency questionnaire used in the 5-year follow-up survey of the JPHC Study: questionnaire structure, computation algorithms, and area-based mean intake. J Epidemiol. 2003; 13(1 Suppl):S13-22. PMC: 9767697. DOI: 10.2188/jea.13.1sup_13. View

12.

Ishihara J, Sobue T, Yamamoto S, Yoshimi I, Sasaki S, Kobayashi M . Validity and reproducibility of a self-administered food frequency questionnaire in the JPHC Study Cohort II: study design, participant profile and results in comparison with Cohort I. J Epidemiol. 2003; 13(1 Suppl):S134-47. PMC: 9767691. DOI: 10.2188/jea.13.1sup_134. View

13.

Linley P, Joseph S . Positive change following trauma and adversity: a review. J Trauma Stress. 2004; 17(1):11-21. DOI: 10.1023/B:JOTS.0000014671.27856.7e. View

14.

Rock C, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya K, Schwartz A . Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin. 2012; 62(4):243-74. DOI: 10.3322/caac.21142. View

15.

Sewitch M, Rajput Y . A literature review of complementary and alternative medicine use by colorectal cancer patients. Complement Ther Clin Pract. 2010; 16(1):52-6. DOI: 10.1016/j.ctcp.2009.10.001. View

16.

Ness S, Kokal J, Fee-Schroeder K, Novotny P, Satele D, Barton D . Concerns across the survivorship trajectory: results from a survey of cancer survivors. Oncol Nurs Forum. 2012; 40(1):35-42. DOI: 10.1188/13.ONF.35-42. View

17.

Wakai K, Kojima M, Nishio K, Suzuki S, Niwa Y, Lin Y . Psychological attitudes and risk of breast cancer in Japan: a prospective study. Cancer Causes Control. 2007; 18(3):259-67. DOI: 10.1007/s10552-006-0111-x. View

18.

Herth K . Abbreviated instrument to measure hope: development and psychometric evaluation. J Adv Nurs. 1992; 17(10):1251-9. DOI: 10.1111/j.1365-2648.1992.tb01843.x. View

19.

Meyerhardt J, Giovannucci E, Holmes M, Chan A, Chan J, Colditz G . Physical activity and survival after colorectal cancer diagnosis. J Clin Oncol. 2006; 24(22):3527-34. DOI: 10.1200/JCO.2006.06.0855. View

20.

Bloom J, Petersen D, Kang S . Multi-dimensional quality of life among long-term (5+ years) adult cancer survivors. Psychooncology. 2007; 16(8):691-706. DOI: 10.1002/pon.1208. View