Neural Activity Predicts Reaction in Primates Long Before a Behavioral Response

Overview

Journal Front Behav Neurosci

Specialty Psychology

Date 2018 Oct 2

PMID 30271333

Citations 8

Authors

Mohsen Parto Dezfouli

Mohammad Bagher Khamechian

Stefan Treue

Moein Esghaei

Mohammad Reza Daliri

Affiliations

Soon will be listed here.

Abstract

How neural activity is linked to behavior is a critical question in neural engineering and cognitive neurosciences. It is crucial to predict behavior as early as possible, to plan a machine response in real-time brain computer interactions. However, previous studies have studied the neural readout of behavior only within a short time before the action is performed. This leaves unclear, if the neural activity long before a decision could predict the upcoming behavior. By recording extracellular neural activities from the visual cortex of behaving rhesus monkeys, we show that: (1) both, local field potentials (LFPs) and the rate of neural spikes long before (>2 s) a monkey responds to a change, foretell its behavioral performance in a spatially selective manner; (2) LFPs, the more accessible component of extracellular activity, are a stronger predictor of behavior; and (3) LFP amplitude is positively correlated while spiking activity is negatively correlated with behavioral reaction time (RT). These results suggest that field potentials could be used to predict behavior way before it is performed, an observation that could potentially be useful for brain computer interface applications, and that they contribute to the sensory neural circuit's speed in information processing.

Citing Articles

Coupled oscillations orchestrate selective information transmission in visual cortex.

Khamechian M, Daliri M, Treue S, Esghaei M PNAS Nexus. 2024; 3(8):pgae288.

PMID: 39161729 PMC: 11331424. DOI: 10.1093/pnasnexus/pgae288.

Deviance Distraction and Stimulus-Specific Adaptation in the Somatosensory Cortex Reduce with Experience.

Ghasemi Nejad N, English G, Apostolelli A, Kopp N, Yanik M, von der Behrens W J Neurosci. 2023; 43(24):4418-4433.

PMID: 37169591 PMC: 10278680. DOI: 10.1523/JNEUROSCI.1714-22.2023.

Frequency modulation of cortical rhythmicity governs behavioral variability, excitability and synchrony of neurons in the visual cortex.

Khamechian M, Daliri M Sci Rep. 2022; 12(1):20914.

PMID: 36463385 PMC: 9719482. DOI: 10.1038/s41598-022-25264-5.

Decoding Adaptive Visuomotor Behavior Mediated by Non-linear Phase Coupling in Macaque Area MT.

Khamechian M, Daliri M Front Neurosci. 2020; 14:230.

PMID: 32317912 PMC: 7147352. DOI: 10.3389/fnins.2020.00230.

Attention strengthens across-trial pre-stimulus phase coherence in visual cortex, enhancing stimulus processing.

Zareian B, Maboudi K, Daliri M, Moghaddam H, Treue S, Esghaei M Sci Rep. 2020; 10(1):4837.

PMID: 32179777 PMC: 7076023. DOI: 10.1038/s41598-020-61359-7.

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