» Articles » PMID: 30228787

Unicentric Castleman Disease Presenting As a Retroperitoneal Peripancreatic Mass: A Report of Two Cases and Review of Literature

Overview
Specialty Gastroenterology
Date 2018 Sep 20
PMID 30228787
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Castleman disease (CD) is a rare disorder of lymph nodes and related tissues. CD generally occurs in the mediastinum, as well as in cervical, retroperitoneal and axillary regions. The disease is classified into two major types: unicentric CD (UCD) and multicentric CD. The occurrence of UCD in the retroperitoneal peripancreatic region is quite rare. We encountered two cases of retroperitoneal peripancreatic UCD in our hospital during the past three years. Following a series of medical examinations, including magnetic resonance imaging, computed tomography, ultrasonography and postoperative histopathological examination, these two patients were diagnosed with UCD, which presented as a retroperitoneal peripancreatic mass. The mass in each patient was completely excised, and no postoperative radiochemotherapy was administered. Both patients recovered well without recurrence during a follow-up period of 30 mo and 8 mo.

Citing Articles

Castleman disease mimicking accessory spleen on imaging: A case report.

Ayoobi Yazdi N, MomeniAmjadi A, Kermanipour R, Alizadeh S, Salahshour F, Tahamtan M Radiol Case Rep. 2024; 20(1):651-656.

PMID: 39583236 PMC: 11585472. DOI: 10.1016/j.radcr.2024.09.143.


Clinical features and outcomes of retroperitoneal unicentric Castleman disease resected as sarcomas: insights from a high-volume sarcoma center.

Gao H, Li W, Zou B, Liu S, Miao C Front Surg. 2024; 11:1371968.

PMID: 39301171 PMC: 11410775. DOI: 10.3389/fsurg.2024.1371968.


Unicentric Castleman Disease: A Rare Diagnosis of Radiological and Histological Correlation.

Maqbool S, Javed A, Idrees T, Anwar S Indian J Otolaryngol Head Neck Surg. 2022; 75(2):975-978.

PMID: 36373120 PMC: 9638322. DOI: 10.1007/s12070-022-03253-4.


Retroperitoneal Unicentric Castleman's disease, a case report.

Yazdi S, Nazar E Ann Med Surg (Lond). 2022; 79:104109.

PMID: 35860095 PMC: 9289496. DOI: 10.1016/j.amsu.2022.104109.


Unicentric Castleman disease: multidetector computed tomography classification with surgical and pathologic correlation.

Sun X, Du Y, Zhang Y, Wang R, Hou D Quant Imaging Med Surg. 2021; 11(8):3562-3568.

PMID: 34341731 PMC: 8245968. DOI: 10.21037/qims-20-1033.


References
1.
Charalabopoulos A, Misiakos E, Foukas P, Tsapralis D, Charalampopoulos A, Liakakos T . Localized peripancreatic plasma cell Castleman disease. Am J Surg. 2010; 199(5):e51-3. DOI: 10.1016/j.amjsurg.2009.05.020. View

2.
Dalla Pria A, Pinato D, Roe J, Naresh K, Nelson M, Bower M . Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients. Blood. 2017; 129(15):2143-2147. DOI: 10.1182/blood-2016-10-747477. View

3.
Musters A, Assaf A, Gerlag D, Tak P, Tas S . Discovery of Innovative Therapies for Rare Immune-Mediated Inflammatory Diseases via Off-Label Prescription of Biologics: The Case of IL-6 Receptor Blockade in Castleman's Disease. Front Immunol. 2015; 6:625. PMC: 4676110. DOI: 10.3389/fimmu.2015.00625. View

4.
Dong A, Dong H, Zuo C . Castleman disease of the porta hepatis mimicking exophytic hepatocellular carcinoma on CT, MRI, and FDG PET/CT. Clin Nucl Med. 2013; 39(1):e69-72. DOI: 10.1097/RLU.0b013e31827a25fd. View

5.
Siegel M, Ghafouri S, Ajmera R, Simon G . Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease. Int J Infect Dis. 2016; 48:49-51. DOI: 10.1016/j.ijid.2016.05.005. View