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Stepwise Extraction of High-value Chemicals from () and an Economic Feasibility Study

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Specialty Biotechnology
Date 2018 Sep 14
PMID 30211017
Citations 7
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Abstract

() consists of diverse high-value chemicals, such as phycocyanin, lipids/total fatty acids (TFA), and polysaccharides, which have been used for food, cosmetic and pharmacological applications. This study compared various stepwise extraction processes for these high-value chemicals. Considering the yield and properties of extracts, the most suitable extraction order was phycocyanin, lipid/TFA and polysaccharides. The yield of the main product (food-grade phycocyanin) was 8.66% of the biomass dry weight, whereas the yields of the subsequent lipid/TFA and polysaccharide coproducts were 3.55% and 0.72%, respectively. The economic analysis showed that producing phycocyanin alone was economically feasible, but producing coproducts (lipid/TFA and polysaccharides) was not. The production cost of phycocyanin was US$ 249.70 kg, which is an encouraging figure for large-scale production. Moreover, the phycocyanin content of materials utilized for extraction should not be lower than 15% of dry weight to ensure positive the net present value (NPV) of investment.

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References
1.
Oliveira E, Rosa G, Moraes M, Pinto L . Characterization of thin layer drying of Spirulina platensis utilizing perpendicular air flow. Bioresour Technol. 2008; 100(3):1297-303. DOI: 10.1016/j.biortech.2008.05.052. View

2.
Plaza M, Herrero M, Cifuentes A, Ibanez E . Innovative natural functional ingredients from microalgae. J Agric Food Chem. 2009; 57(16):7159-70. DOI: 10.1021/jf901070g. View

3.
Liu L, Chen X, Zhang X, Zhang Y, Zhou B . One-step chromatography method for efficient separation and purification of R-phycoerythrin from Polysiphonia urceolata. J Biotechnol. 2005; 116(1):91-100. DOI: 10.1016/j.jbiotec.2004.09.017. View

4.
Chaiklahan R, Chirasuwan N, Triratana P, Loha V, Tia S, Bunnag B . Polysaccharide extraction from Spirulina sp. and its antioxidant capacity. Int J Biol Macromol. 2013; 58:73-8. DOI: 10.1016/j.ijbiomac.2013.03.046. View

5.
Moraes C, Kalil S . Strategy for a protein purification design using C-phycocyanin extract. Bioresour Technol. 2009; 100(21):5312-7. DOI: 10.1016/j.biortech.2009.05.026. View