Identification of a Bromodomain-containing Protein 2 Gene Polymorphic Variant and Its Effects on Pork Quality Traits in Berkshire Pigs
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Bromodomain-containing protein 2 is a nuclear serine/threonine kinase involved in transcriptional regulation. We investigated the expression and association of the gene as a candidate gene for meat quality traits in Berkshire pigs. mRNA was expressed at relatively high levels in muscle tissue. Statistical analysis revealed that the c.1709G>C polymorphism of the gene was significantly associated with carcass weight, meat color (a*, redness), protein content, cooking loss, water-holding capacity, carcass temperatures 4, 12 and 24 h postmortem, and the 24 h postmortem pH in 384 Berkshire pigs. Therefore, this polymorphism in the porcine gene may be used as a candidate genetic marker to improve meat quality traits in pigs.
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Wang N, Wu R, Tang D, Kang R Signal Transduct Target Ther. 2021; 6(1):23.
PMID: 33462181 PMC: 7813845. DOI: 10.1038/s41392-020-00384-4.