Similar Hematologic and Nutritional Outcomes After Proximal Gastrectomy with Double-tract Reconstruction in Comparison to Total Gastrectomy for Early Upper Gastric Cancer

Overview

Journal Surg Endosc

Publisher Springer

Specialties Gastroenterology
General Surgery
Radiology

Date 2018 Sep 12

PMID 30203207

Citations 32

Authors

Minah Cho

Taeil Son

Hyoung-Il Kim

Sung Hoon Noh

Seohee Choi

Won Jun Seo

Chul Kyu Roh

Woo Jin Hyung

Affiliations

Soon will be listed here.

Abstract

Background: Proximal gastrectomy offers theoretical benefits over total gastrectomy in terms of hematologic and nutritional outcomes. However, little evidence confirming these benefits has been reported. The aim of this study was to assess the hematologic and nutritional outcomes of proximal gastrectomy with double-tract reconstruction in comparison to those of total gastrectomy.

Methods: We retrospectively analyzed data from 80 patients with stage I gastric cancer who underwent proximal gastrectomy with double-tract reconstruction (n = 38) or total gastrectomy (n = 42) from September 2014 to December 2015. We compared hematologic (including hemoglobin, ferritin, vitamin B, etc.) and nutritional outcomes [including body mass index (BMI), serum total protein, albumin, total cholesterol, and total lymphocyte count] between the two groups.

Results: We found no significant differences in changes in hemoglobin (P = 0.250) or cumulative incidence of iron deficiency anemia (P = 0.971) during a median follow-up period of 24 months (range 18-30 months) after surgery. Cumulative incidence of vitamin B deficiency also did not differ significantly between the proximal and total gastrectomy groups (P = 0.087). BMI changes from baseline were not significantly different between the two groups (P = 0.591). Likewise, there were no statistically significant differences in nutritional outcomes.

Conclusions: Proximal gastrectomy with double-tract reconstruction exhibited similar outcomes in terms of hematologic and nutritional features in comparison to total gastrectomy.

Citing Articles

Korean Practice Guidelines for Gastric Cancer 2024: An Evidence-based, Multidisciplinary Approach (Update of 2022 Guideline).

Kim I, Kang S, Choi W, Seo A, Eom B, Kang B J Gastric Cancer. 2025; 25(1):5-114.

PMID: 39822170 PMC: 11739648. DOI: 10.5230/jgc.2025.25.e11.

Proximal Gastrectomy Is Associated with Lower Incidence of Anemia and Vitamin B12 Deficiency Compared to Total Gastrectomy in Patients with Upper Gastric Cancer.

Song J, Park S, Cho M, Kim Y, Hyung W, Kim H Cancer Res Treat. 2024; 57(1):174-185.

PMID: 38965924 PMC: 11729319. DOI: 10.4143/crt.2024.319.

Comparing the antireflux effect of laparoscopic proximal gastrectomy with double-flap technique reconstruction versus laparoscopic total gastrectomy with Roux-en-Y reconstruction for proximal early gastric cancer: study protocol for a multicentre,....

Zhou S, Xie Y, Zhu Y, Tan J, Yang B, Zhong L BMJ Open. 2024; 14(7):e079940.

PMID: 38964794 PMC: 11227769. DOI: 10.1136/bmjopen-2023-079940.

Impact of malnutrition and nutritional support after gastrectomy in patients with gastric cancer.

Kang M, Lee H Ann Gastroenterol Surg. 2024; 8(4):534-552.

PMID: 38957563 PMC: 11216795. DOI: 10.1002/ags3.12788.

Food passage following proximal gastrectomy with double-tract reconstruction and its effect on nutritional status in early gastric cancer: a prospective single-center cohort study.

Park J, Park K, Lee S, Chung H, Jeong S, Lee S Ann Surg Treat Res. 2024; 106(6):313-321.

PMID: 38868586 PMC: 11164659. DOI: 10.4174/astr.2024.106.6.313.

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