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Immune Function: Impact of Exercise and Nutritional Interventions

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Publisher Sage Publications
Date 2018 Sep 12
PMID 30202270
Citations 1
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Abstract

This article provides a brief commentary on the accompanying article, "Nutrition and Physical Activity Interventions to Improve Immunity" by Davison, Kehaya, and Jones. The article reviews the evidence on physical exercise and/or nutrition in modulating immune response, with a specific focus on the prevention of respiratory infection. Given the large scope of the review, an overview of current findings is presented, rather than in-depth discussions, and the nutritional strategies discussed tend to focus on the strategies that have been studied in the context of exercise. Some further insight is provided in the commentary on potential mechanisms that may explain the benefits of exercise, a brief discussion on the impact of obesity and host defense, and future directions for research. In general, the article sufficiently describes the current evidence, and draws appropriate conclusions based on the evidence presented. The article is recommended for audiences that have limited background on these topics, and for those who are familiar with this line of research.

Citing Articles

The impact of supervised physical exercise on chemokines and cytokines in recovered COVID-19 patients.

Filgueira T, Carvalho P, de Sousa Fernandes M, Castoldi A, Teixeira A, de Albuquerque R Front Immunol. 2023; 13:1051059.

PMID: 36685603 PMC: 9846636. DOI: 10.3389/fimmu.2022.1051059.

References
1.
Sim Y, Yu S, Yoon K, Yoon K, Loiacono C, Kohut M . Chronic exercise reduces illness severity, decreases viral load, and results in greater anti-inflammatory effects than acute exercise during influenza infection. J Infect Dis. 2009; 200(9):1434-42. PMC: 2812897. DOI: 10.1086/606014. View

2.
Wilkinson T, Li C, Chui C, Huang A, Perkins M, Liebner J . Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. Nat Med. 2012; 18(2):274-80. DOI: 10.1038/nm.2612. View

3.
Louie J, Acosta M, Samuel M, Schechter R, Vugia D, Harriman K . A novel risk factor for a novel virus: obesity and 2009 pandemic influenza A (H1N1). Clin Infect Dis. 2011; 52(3):301-12. DOI: 10.1093/cid/ciq152. View

4.
Smith T, Kennedy S, Fleshner M . Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men. J Appl Physiol (1985). 2004; 97(2):491-8. DOI: 10.1152/japplphysiol.01404.2003. View

5.
Kohut M, Cooper M, Nickolaus M, Russell D, Cunnick J . Exercise and psychosocial factors modulate immunity to influenza vaccine in elderly individuals. J Gerontol A Biol Sci Med Sci. 2002; 57(9):M557-62. DOI: 10.1093/gerona/57.9.m557. View