Nutritional Immunity: Starving Pathogens of Trace Minerals

Overview

Journal Am J Lifestyle Med

Publisher Sage Publications

Date 2018 Sep 12

PMID 30202269

Citations 62

Authors

Stephen R Hennigar

James P McClung

Affiliations

Soon will be listed here.

Abstract

Nutritional immunity is a process by which a host organism sequesters trace minerals in an effort to limit pathogenicity during infection. Circulating concentrations of minerals, such as iron and zinc, decline rapidly and dramatically with the inflammation associated with infection. The decline in iron and zinc is thought to starve invading pathogens of these essential elements, limiting disease progression and severity. The mechanisms contributing to the hypoferremia and hypozincemia of inflammation and potential interventions that exploit this process for the management of infection will be discussed.

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