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Lentigo Maligna and Lentigo Maligna Melanoma: Contemporary Issues in Diagnosis and Management

Overview
Journal Melanoma Manag
Date 2018 Sep 8
PMID 30190846
Citations 7
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Abstract

Lentigo maligna and lentigo maligna melanomas present diagnostic and treatment dilemmas due to their frequent presence within a background of sun-damaged skin, and their location on cosmetically and functionally sensitive areas. As the incidence of this entity is increasing, diagnostic and management controversies have developed. While surgery remains the gold standard of treatment, nonsurgical treatment options are also emerging for both adjunctive and primary therapy.

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References
1.
Nadiminti H, Scope A, Marghoob A, Busam K, Nehal K . Use of reflectance confocal microscopy to monitor response of lentigo maligna to nonsurgical treatment. Dermatol Surg. 2009; 36(2):177-84. DOI: 10.1111/j.1524-4725.2009.01421.x. View

2.
Kvaskoff M, Siskind V, Green A . Risk factors for lentigo maligna melanoma compared with superficial spreading melanoma: a case-control study in Australia. Arch Dermatol. 2011; 148(2):164-70. DOI: 10.1001/archdermatol.2011.291. View

3.
Bowen A, Thacker B, Goldgar D, Bowen G . Immunohistochemical staining with Melan-A of uninvolved sun-damaged skin shows features characteristic of lentigo maligna. Dermatol Surg. 2011; 37(5):657-63. DOI: 10.1111/j.1524-4725.2011.01946.x. View

4.
Gaudy-Marqueste C, Perchenet A, Tasei A, Madjlessi N, Magalon G, Richard M . The "spaghetti technique": an alternative to Mohs surgery or staged surgery for problematic lentiginous melanoma (lentigo maligna and acral lentiginous melanoma). J Am Acad Dermatol. 2010; 64(1):113-8. DOI: 10.1016/j.jaad.2010.03.014. View

5.
Erickson C, Miller S . Treatment options in melanoma in situ: topical and radiation therapy, excision and Mohs surgery. Int J Dermatol. 2010; 49(5):482-91. DOI: 10.1111/j.1365-4632.2010.04423.x. View