A Metabolic Vulnerability of Small-cell Lung Cancer

Overview

Journal Oncotarget

Specialty Oncology

Date 2018 Sep 8

PMID 30190785

Citations 9

Authors

Miyuki Nomura

Mami Morita

Nobuhiro Tanuma

Affiliations

Soon will be listed here.

Citing Articles

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Actionable Driver Events in Small Cell Lung Cancer.

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MicroRNA and Metabolic Profiling of a Primary Ovarian Neuroendocrine Carcinoma Pulmonary-Type Reveals a High Degree of Similarity with Small Cell Lung Cancer.

Miglietta S, Girolimetti G, Marchio L, Sollazzo M, Laprovitera N, Coluccelli S Noncoding RNA. 2022; 8(5).

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Progression and metastasis of small cell lung carcinoma: the role of the PI3K/Akt/mTOR pathway and metabolic alterations.

Krencz I, Sztankovics D, Danko T, Sebestyen A, Khoor A Cancer Metastasis Rev. 2021; 40(4):1141-1157.

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References

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Christofk H, Vander Heiden M, Harris M, Ramanathan A, Gerszten R, Wei R . The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature. 2008; 452(7184):230-3. DOI: 10.1038/nature06734. View

Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R . PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth. Cancer Cell. 2018; 33(3):355-367.e7. DOI: 10.1016/j.ccell.2018.02.004. View

Martinez-Reyes I, Chandel N . Waste Not, Want Not: Lactate Oxidation Fuels the TCA Cycle. Cell Metab. 2017; 26(6):803-804. DOI: 10.1016/j.cmet.2017.11.005. View

George J, Lim J, Jang S, Cun Y, Ozretic L, Kong G . Comprehensive genomic profiles of small cell lung cancer. Nature. 2015; 524(7563):47-53. PMC: 4861069. DOI: 10.1038/nature14664. View