Coronary Artery Calcium and Intima-media Thickness Are Associated with Level of Cytomegalovirus Immunoglobulin G in HIV-infected Patients

Overview

Journal HIV Med

Publisher Wiley

Specialty Infectious Diseases

Date 2018 Sep 6

PMID 30182478

Citations 7

Authors

A Knudsen

U S Kristoffersen

I Panum

Y B Hansen

P D Skottrup

P Hasbak

A Kjaer

A-M Lebech

Affiliations

Soon will be listed here.

Abstract

Coinfection with cytomegalovirus (CMV) may be involved in cardiovascular disease in HIV-infected patients. We found that higher level of CMV immunoglobulin G (IgG) was independently associated with an increased risk of coronary artery calcium and higher intima-media thickness in HIV-infected patients but not in healthy controls after adjustment for other cardiovascular risk factors and levels of herpes viridae IgG.

Citing Articles

Cytomegalovirus Antibodies and Coronary Artery Disease in People with HIV: A Cohort Study.

Suarez-Zdunek M, Knudsen A, Fuchs A, Kirkby N, Benfield T, Gerstoft J Viruses. 2025; 17(2).

PMID: 40006986 PMC: 11860406. DOI: 10.3390/v17020231.

Advances in the Management of Cardiovascular Disease in the Setting of Human Immunodeficiency Virus.

Durstenfeld M, Hsue P Infect Dis Clin North Am. 2024; 38(3):517-530.

PMID: 38871571 PMC: 11305916. DOI: 10.1016/j.idc.2024.04.006.

Cytomegalovirus Immunoglobulin G Levels and Subclinical Arterial Disease among People Living with HIV in Botswana: A Cross-Sectional Study.

Moshomo T, Molefe-Baikai O, Bennett K, Gaolathe T, Moyo S, Gaseitsewe S Biomedicines. 2024; 12(5).

PMID: 38790897 PMC: 11118051. DOI: 10.3390/biomedicines12050935.

The Role of CMV Infection in Primary Lesions, Development and Clinical Expression of Atherosclerosis.

Cristescu C, Alain S, Ruta S J Clin Med. 2022; 11(13).

PMID: 35807114 PMC: 9267753. DOI: 10.3390/jcm11133832.

Cytomegalovirus may influence vascular endothelial health in Indonesian HIV-infected patients after 5 years on ART.

Wijaya I, Karim B, Azizi M, Ariyanto I, Mansjoer A, Yunihastuti E AIDS Res Ther. 2021; 18(1):83.

PMID: 34763708 PMC: 8582163. DOI: 10.1186/s12981-021-00410-7.