A Routine Method for the Establishment of Permanent Growing Lymphoblastoid Cell Lines

Overview

Journal Hum Genet

Specialty Genetics

Date 1986 Aug 1

PMID 3017841

Citations 240

Authors

H Neitzel

Affiliations

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Abstract

Permanent lymphoblastoid cell lines are of great practical value in human clinical and experimental genetics. A detailed protocol for routine use is given for the establishment of lymphoblastoid lines from peripheral blood using Epstein-Barr virus and the immunosuppressivum Cyclosporin A. In addition, the biologic basis of this transformation system is briefly summarized.

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