Rainer W. Guillery and the Genetic Analysis of Brain Development

Overview

Journal Eur J Neurosci

Specialty Neurology

Date 2018 Aug 29

PMID 30152010

Citations 2

Authors

Christopher A Walsh

Affiliations

Soon will be listed here.

Abstract

Ray Guillery had broad research interests that spanned cellular neuroanatomy, but was perhaps best known for his investigation of the connectivity and function of the thalamus, especially the visual pathways. His work on the genetics of abnormal vision in albino mammals served as an early paradigm for genetic approaches for studying brain connectivity of complex species in general, and remains of major relevance today. This work, especially on the Siamese cat, illustrates the complex relationship between genotype and physiology of cerebral cortical circuits, and anticipated many of the issues underlying the imperfect relationship between genes, circuits, and behavior in mammalian species including human. This review also briefly summarizes studies from our own lab inspired by Ray Guillery's legacy that continues to explore the relationship between genes, structure, and behavior in human cerebral cortex.

Citing Articles

Conversations with Ray Guillery on albinism: linking Siamese cat visual pathway connectivity to mouse retinal development.

Mason C, Guillery R Eur J Neurosci. 2019; 49(7):913-927.

PMID: 30801828 PMC: 6697109. DOI: 10.1111/ejn.14396.

Cortical layer with no known function.

Molnar Z Eur J Neurosci. 2018; 49(7):957-963.

PMID: 29806977 PMC: 7217175. DOI: 10.1111/ejn.13978.

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