Digital Pathology Image Analysis: Opportunities and Challenges

Overview

Journal Imaging Med

Specialty Radiology

Date 2018 Aug 28

PMID 30147749

Citations 51

Authors

Anant Madabhushi

Affiliations

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References

Gurcan M, Kong J, Sertel O, Cambazoglu B, Saltz J, Catalyurek U . Computerized pathological image analysis for neuroblastoma prognosis. AMIA Annu Symp Proc. 2008; :304-8. PMC: 2655895. View

Ruiz A, Sertel O, Ujaldon M, Catalyurek U, Saltz J, Gurcan M . Stroma classification for neuroblastoma on graphics processors. Int J Data Min Bioinform. 2009; 3(3):280-98. DOI: 10.1504/ijdmb.2009.026702. View

Anderson N, Hamilton P, Bartels P, Thompson D, Montironi R, Sloan J . Computerized scene segmentation for the discrimination of architectural features in ductal proliferative lesions of the breast. J Pathol. 1997; 181(4):374-80. DOI: 10.1002/(SICI)1096-9896(199704)181:4<374::AID-PATH795>3.0.CO;2-N. View

Dey P, Mohanty S . Fractal dimensions of breast lesions on cytology smears. Diagn Cytopathol. 2003; 29(2):85-6. DOI: 10.1002/dc.10324. View

Contesso G, Mouriesse H, Friedman S, Genin J, Sarrazin D, Rouesse J . The importance of histologic grade in long-term prognosis of breast cancer: a study of 1,010 patients, uniformly treated at the Institut Gustave-Roussy. J Clin Oncol. 1987; 5(9):1378-86. DOI: 10.1200/JCO.1987.5.9.1378. View

Allsbrook Jr W, Mangold K, Johnson M, LANE R, LANE C, Epstein J . Interobserver reproducibility of Gleason grading of prostatic carcinoma: general pathologist. Hum Pathol. 2001; 32(1):81-8. DOI: 10.1053/hupa.2001.21135. View

Boccignone G, Napoletano P, Caggiano V, Ferraro M . A multiresolution diffused expectation-maximization algorithm for medical image segmentation. Comput Biol Med. 2005; 37(1):83-96. DOI: 10.1016/j.compbiomed.2005.10.002. View

Lexe G, Monaco J, Doyle S, Basavanhally A, Reddy A, Seiler M . Towards improved cancer diagnosis and prognosis using analysis of gene expression data and computer aided imaging. Exp Biol Med (Maywood). 2009; 234(8):860-79. DOI: 10.3181/0902-MR-89. View

Fukagai T, Namiki T, Namiki H, Carlile R, Shimada M, Yoshida H . Discrepancies between Gleason scores of needle biopsy and radical prostatectomy specimens. Pathol Int. 2001; 51(5):364-70. DOI: 10.1046/j.1440-1827.2001.01207.x. View

10.

Bostwick D . Gleason grading of prostatic needle biopsies. Correlation with grade in 316 matched prostatectomies. Am J Surg Pathol. 1994; 18(8):796-803. DOI: 10.1097/00000478-199408000-00006. View

11.

Glaessgen A, Hamberg H, Pihl C, Sundelin B, Nilsson B, Egevad L . Interobserver reproducibility of percent Gleason grade 4/5 in total prostatectomy specimens. J Urol. 2002; 168(5):2006-10. DOI: 10.1016/S0022-5347(05)64283-8. View

12.

Engers R . Reproducibility and reliability of tumor grading in urological neoplasms. World J Urol. 2007; 25(6):595-605. DOI: 10.1007/s00345-007-0209-0. View

13.

Qureshi H, Sertel O, Rajpoot N, Wilson R, Gurcan M . Adaptive discriminant wavelet packet transform and local binary patterns for meningioma subtype classification. Med Image Comput Comput Assist Interv. 2008; 11(Pt 2):196-204. DOI: 10.1007/978-3-540-85990-1_24. View

14.

Bostwick D . Grading prostate cancer. Am J Clin Pathol. 1994; 102(4 Suppl 1):S38-56. View

15.

Lenkinski R, Bloch B, Liu F, Frangioni J, Perner S, Rubin M . An illustration of the potential for mapping MRI/MRS parameters with genetic over-expression profiles in human prostate cancer. MAGMA. 2008; 21(6):411-21. PMC: 2739832. DOI: 10.1007/s10334-008-0133-3. View

16.

Anderson T, Sufi F, Ellis I, Sloane J, Moss S . Implications of pathologist concordance for breast cancer assessments in mammography screening from age 40 years. Hum Pathol. 2002; 33(3):365-71. DOI: 10.1053/hupa.2002.32222. View

17.

Kong J, Sertel O, Boyer K, Saltz J, Gurcan M, Shimada H . Computer-assisted grading of neuroblastic differentiation. Arch Pathol Lab Med. 2008; 132(6):903-4. DOI: 10.5858/2008-132-903-CGOND. View

18.

Jafari-Khouzani K, Soltanian-Zadeh H . Multiwavelet grading of pathological images of prostate. IEEE Trans Biomed Eng. 2003; 50(6):697-704. DOI: 10.1109/TBME.2003.812194. View

19.

Tabesh A, Teverovskiy M, Pang H, Kumar V, Verbel D, Kotsianti A . Multifeature prostate cancer diagnosis and Gleason grading of histological images. IEEE Trans Med Imaging. 2007; 26(10):1366-78. DOI: 10.1109/TMI.2007.898536. View

20.

Doyle S, Rodriguez C, Madabhushi A, Tomaszeweski J, Feldman M . Detecting prostatic adenocarcinoma from digitized histology using a multi-scale hierarchical classification approach. Conf Proc IEEE Eng Med Biol Soc. 2007; 2006:4759-62. DOI: 10.1109/IEMBS.2006.260188. View