Differences in Energy and Corneal Endothelium Between Femtosecond Laser-assisted and Conventional Cataract Surgeries: Prospective, Intraindividual, Randomized Controlled Trial

Overview

Journal Int J Ophthalmol

Specialty Ophthalmology

Date 2018 Aug 25

PMID 30140634

Citations 17

Authors

Lucia Bascaran

Txomin Alberdi

Itziar Martinez-Soroa

Cristina Sarasqueta

Javier Mendicute

Affiliations

Soon will be listed here.

Abstract

Aim: To compare intraoperative phacoemulsification parameters and its effect on the corneal endothelium of eyes undergoing femtosecond laser-assisted cataract surgery (FLACS) versus conventional phacoemulsification (CP) cataract surgery.

Methods: Two hundred eyes from one hundred patients were included in a prospective, non-blinded, randomized, controlled, intraindividual clinical study. One hundred eyes underwent FLACS while their one hundred fellow eyes underwent CP. All surgeries were performed using the Victus femtosecond laser platform and Infinity Vision System phacoemulsification machine. Primary outcome measure was endothelial cell density 6mo after surgery. Secondary outcome measures included central corneal thickness (CCT), average cell area, standard deviation, coefficient of variation and hexagonality before surgery and 6mo after surgery and endothelial cell density loss during this period were also evaluated. Intraoperative efficiency parameters [cumulative dissipated energy (CDE), total intraocular surgery time, total ultrasound time, total phacoemulsification time, total torsional energy time, total aspiration time, ultrasound energy, torsional amplitude and fluid required during surgery] were also collated.

Results: Data from these patients was not considered for analysis. Data from 92 patients were analysed. Postoperative endothelial cell density (cells/mm) between groups (2211.88±392.49 CP; 2246.31±403.48 FLACS) was not statistically significant (=0.869). Total ultrasound time, torsional energy time, CDE and fluid requirements were significantly lower the FLACS group (<0.05). Other parameters did not show statistically significant difference between FLACS and CP.

Conclusion: FLACS displays significant improvements in phacoemulsification parameters in comparison to CP. There are no significant differences in corneal endothelium measures between FLACS and CP.

Citing Articles

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Comparison of corneal endothelial cell loss in FLACS: impact on endothelial cells in different regions.

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Narrative review after post-hoc trial analysis of factors that predict corneal endothelial cell loss after phacoemulsification: Tips for improving cataract surgery research.

Perone J, Luc M, Zevering Y, Vermion J, Gan G, Goetz C PLoS One. 2024; 19(3):e0298795.

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Salgado R, Torres P, Marinho A Clin Ophthalmol. 2024; 18:459-472.

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