Ki-67: More Hidden Behind a 'Classic Proliferation Marker'

Overview

Journal Trends Biochem Sci

Specialty Biochemistry

Date 2018 Aug 23

PMID 30131191

Citations 37

Authors

Raquel Sales Gil

Paola Vagnarelli

Affiliations

Soon will be listed here.

Abstract

Nuclear antigen Ki-67 is widely accepted as a cell proliferation marker in both research and cancer diagnostic settings. Despite its extensive use and clinical value, very little is still known about the biological function of Ki-67. A recent work published in Cell Reports has revealed important novel aspects of Ki-67 regulation that could provide new and extended prognostic and therapeutic value.

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