New Adenovirus Groups in Western Palaearctic Bats

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2018 Aug 22

PMID 30127258

Citations 11

Authors

Maria Iglesias-Caballero

Javier Juste

Sonia Vazquez-Moron

Ana Falcon

Carolina Aznar-Lopez

Carlos Ibanez

Francisco Pozo

Guillermo Ruiz

Jose M Berciano

Inazio Garin

Joxerra Aihartza

Juan E Echevarria

Inmaculada Casas

Affiliations

Soon will be listed here.

Abstract

In the context of long-term screening for viruses on Western Palaearctic bats, we tested for the presence of adenovirus 1392 oropharyngeal swabs and 325 stool samples taken from 27 bat species. Adenoviruses were detected in 12 species of the Vespertilionidae and the Rhinolophidae families. Fifty positive respiratory and 26 positive stool samples were studied. Phylogenetic analyses of partial hexon protein and partial DNA-dependent DNA polymerase genes indicate that all these bat adenoviruses belong to the genus but without constituting a monophyletic cluster. According to genetic identities, the new groups are distinct to the previously described and species and contribute with potentially new members. Our data support that diversity of bat mastadenovirus is host-dependent and increase the knowledge of potentially pathogenic virus from bats. Due to the active role of bats as viral reservoirs, the characterization of these viruses is relevant for Public Health.

Citing Articles

Infection by Adenovirus Type 2 in a Short-Tailed Bat in Mexico.

Trejo-Chavez A, Castillo-Velazquez U, Mendez-Bernal A, Flores-Martinez K, Hernandez-Vidal G, Rodriguez-Tovar L Case Rep Vet Med. 2025; 2025:2431526.

PMID: 40041451 PMC: 11876517. DOI: 10.1155/crve/2431526.

A Novel Mastadenovirus from Which Represents a Distinct Evolutionary Branch of Viruses from Bats in Europe.

Speranskaya A, Dorokhin A, Korneenko E, Chudinov I, Samoilov A, Kruskop S Viruses. 2024; 16(8).

PMID: 39205181 PMC: 11359159. DOI: 10.3390/v16081207.

Evaluation of Mastadenovirus and Rotavirus Presence in Phyllostomid, Vespertilionid, and Molossid Bats Captured in Rio Grande do Sul, Southern Brazil.

Sita A, Birlem G, de Souza da Silva D, Possamai G, Petry K, de Almeida P Food Environ Virol. 2024; 16(2):136-142.

PMID: 38532064 DOI: 10.1007/s12560-023-09575-y.

Genetic diversity of adenovirus in neotropical bats from Brazil.

Rizotto L, Bueno L, Correa T, de Moraes M, de Oliveira Viana A, Silva L Braz J Microbiol. 2023; 54(4):3221-3230.

PMID: 37653362 PMC: 10689316. DOI: 10.1007/s42770-023-01109-9.

Morphological and genomic characteristics of two novel actinomycetes, sp. nov. and sp. nov. isolated from bat faeces ( and ).

Huang Y, Zhang S, Tao Y, Yang J, Lu S, Jin D Front Cell Infect Microbiol. 2023; 13:1093407.

PMID: 36864884 PMC: 9973731. DOI: 10.3389/fcimb.2023.1093407.

References

Baker K, Leggett R, Bexfield N, Alston M, Daly G, Todd S . Metagenomic study of the viruses of African straw-coloured fruit bats: detection of a chiropteran poxvirus and isolation of a novel adenovirus. Virology. 2013; 441(2):95-106. PMC: 3667569. DOI: 10.1016/j.virol.2013.03.014. View

de Sales Lima F, Cibulski S, Elesbao F, Carnieli Junior P, Batista H, Roehe P . First detection of adenovirus in the vampire bat (Desmodus rotundus) in Brazil. Virus Genes. 2013; 47(2):378-81. PMC: 7088603. DOI: 10.1007/s11262-013-0947-6. View

Drexler J, Corman V, Wegner T, Tateno A, Zerbinati R, Gloza-Rausch F . Amplification of emerging viruses in a bat colony. Emerg Infect Dis. 2011; 17(3):449-56. PMC: 3165994. DOI: 10.3201/eid1703.100526. View

Waruhiu C, Ommeh S, Obanda V, Agwanda B, Gakuya F, Ge X . Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virol Sin. 2017; 32(2):101-114. PMC: 6702250. DOI: 10.1007/s12250-016-3930-2. View

Hackenbrack N, Rogers M, Ashley R, Keel M, Kubiski S, Bryan J . Evolution and Cryo-electron Microscopy Capsid Structure of a North American Bat Adenovirus and Its Relationship to Other Mastadenoviruses. J Virol. 2016; 91(2). PMC: 5215340. DOI: 10.1128/JVI.01504-16. View

Tan B, Yang X, Ge X, Peng C, Zhang Y, Zhang L . Novel bat adenoviruses with an extremely large E3 gene. J Gen Virol. 2016; 97(7):1625-1635. DOI: 10.1099/jgv.0.000470. View

Maeda K, Hondo E, Terakawa J, Kiso Y, Nakaichi N, Endoh D . Isolation of novel adenovirus from fruit bat (Pteropus dasymallus yayeyamae). Emerg Infect Dis. 2008; 14(2):347-9. PMC: 2630045. DOI: 10.3201/eid1402.070932. View

Roberts D, Nanda A, Havenga M, Abbink P, Lynch D, Ewald B . Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity. Nature. 2006; 441(7090):239-43. DOI: 10.1038/nature04721. View

Tan B, Yang X, Ge X, Peng C, Liu H, Zhang Y . Novel bat adenoviruses with low G+C content shed new light on the evolution of adenoviruses. J Gen Virol. 2017; 98(4):739-748. DOI: 10.1099/jgv.0.000739. View

10.

Ceballos N, Vazquez Moron S, Berciano J, Nicolas O, Lopez C, Juste J . Novel lyssavirus in bat, Spain. Emerg Infect Dis. 2013; 19(5):793-5. PMC: 3647500. DOI: 10.3201/eid1905.121071. View

11.

Calisher C, Childs J, Field H, Holmes K, Schountz T . Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev. 2006; 19(3):531-45. PMC: 1539106. DOI: 10.1128/CMR.00017-06. View

12.

Kajon A, Dickson L, Murtagh P, Viale D, Carballal G, Echavarria M . Molecular characterization of an adenovirus 3-16 intertypic recombinant isolated in Argentina from an infant hospitalized with acute respiratory infection. J Clin Microbiol. 2010; 48(4):1494-6. PMC: 2849541. DOI: 10.1128/JCM.02289-09. View

13.

Pozo F, Juste J, Vazquez-Moron S, Aznar-Lopez C, Ibanez C, Garin I . Identification of Novel Betaherpesviruses in Iberian Bats Reveals Parallel Evolution. PLoS One. 2016; 11(12):e0169153. PMC: 5201282. DOI: 10.1371/journal.pone.0169153. View

14.

Kohl C, Vidovszky M, Muhldorfer K, Dabrowski P, Radonic A, Nitsche A . Genome analysis of bat adenovirus 2: indications of interspecies transmission. J Virol. 2011; 86(3):1888-92. PMC: 3264355. DOI: 10.1128/JVI.05974-11. View

15.

Aznar-Lopez C, Vazquez-Moron S, Marston D, Juste J, Ibanez C, Berciano J . Detection of rhabdovirus viral RNA in oropharyngeal swabs and ectoparasites of Spanish bats. J Gen Virol. 2012; 94(Pt 1):69-75. DOI: 10.1099/vir.0.046490-0. View

16.

Ogawa H, Kajihara M, Nao N, Shigeno A, Fujikura D, Hangombe B . Characterization of a Novel Bat Adenovirus Isolated from Straw-Colored Fruit Bat (Eidolon helvum). Viruses. 2017; 9(12). PMC: 5744146. DOI: 10.3390/v9120371. View

17.

Janoska M, Vidovszky M, Molnar V, Liptovszky M, Harrach B, Benko M . Novel adenoviruses and herpesviruses detected in bats. Vet J. 2010; 189(1):118-21. DOI: 10.1016/j.tvjl.2010.06.020. View

18.

Vazquez-Moron S, Juste J, Ibanez C, Ruiz-Villamor E, Avellon A, Vera M . Endemic circulation of European bat lyssavirus type 1 in serotine bats, Spain. Emerg Infect Dis. 2008; 14(8):1263-6. PMC: 2600403. DOI: 10.3201/eid1408.080068. View

19.

Wong S, Lau S, Woo P, Yuen K . Bats as a continuing source of emerging infections in humans. Rev Med Virol. 2006; 17(2):67-91. PMC: 7169091. DOI: 10.1002/rmv.520. View

20.

Casas I, Powell L, Klapper P, Cleator G . New method for the extraction of viral RNA and DNA from cerebrospinal fluid for use in the polymerase chain reaction assay. J Virol Methods. 1995; 53(1):25-36. DOI: 10.1016/0166-0934(94)00173-e. View