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Correlations Between T-cell Specificity and the Structure of the Antigen Receptor

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Journal Nature
Specialty Science
Date 1986 May 15
PMID 3012351
Citations 124
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Abstract

The derived amino-acid sequences of the heterodimeric antigen receptors expressed by a series of murine T-cell clones are presented. A comparison of the receptor sequences indicates that several mechanisms for generating receptor diversity can influence T-cell specificity, including junctional diversity, combinatorial joining, and combinatorial chain associations.

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