Predictive Value of Red Cell Distribution Width on Left Atrial Thrombus or Left Atrial Spontaneous Echo Contrast in Patients with Non-valvular Atrial Fibrillation

Overview

Journal J Geriatr Cardiol

Specialty Geriatrics

Date 2018 Aug 16

PMID 30108612

Citations 7

Authors

Xian-Zhang Zhan

Wei-Dong Lin

Fang-Zhou Liu

Yu-Mei Xue

Hong-Tao Liao

Xin Li

Xian-Hong Fang

Hai Deng

Jun Huang

Yang-Qiu Li

Jo-Jo Hai

Hung-Fat Tse

Shu-Lin Wu

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the predictive value of red cell distribution width (RDW) on left atrial thrombus (LAT) or left atrial spontaneous echo contrast (LASEC) in patients with non-valvular atrial fibrillation (AF).

Methods: We reviewed 692 patients who were diagnosed as non-valvular AF and underwent transesophageal echocardiography (TEE) in Guangdong Cardiovascular Institute from April 2014 to December 2015. The baseline clinical characteristics, laboratory test of blood routine, electrocardiograph measurements were analyzed.

Results: Eighty-four patients were examined with LAT/LASEC under TEE. The mean RDW level was significantly higher in LAT/LASEC patients compared with the non-LAT/LASEC patients (13.59% ± 1.07% . 14.34% ± 1.34%; < 0.001). Receiver-operating characteristic curve analysis was performed and indicated the best RDW cut point was 13.16%. Furthermore, multivariate logistic regression analysis indicated that RDW level > 13.16% could be an independent risk factor for LAT/LASEC in patients with AF.

Conclusion: Elevated RDW level is associated with the presence of LAT/LASEC and could be with moderate predictive value for LAT/LASEC in patients with non-valvular AF.

Citing Articles

Red Blood Cell Distribution Width is a Biomarker of Red Cell Dysfunction Associated with High Systemic Inflammation and a Prognostic Marker in Heart Failure and Cardiovascular Disease: A Potential Predictor of Atrial Fibrillation Recurrence.

Garcia-Escobar A, Lazaro-Garcia R, Goicolea-Ruigomez J, Gonzalez-Casal D, Fontenla-Cerezuela A, Soto N High Blood Press Cardiovasc Prev. 2024; 31(5):437-449.

PMID: 39031283 DOI: 10.1007/s40292-024-00662-0.

Enhancing the evaluation of acute ischemic stroke risk in individuals with non-valvular atrial fibrillation by including laboratory indicators.

Hou X, Zhang X Sci Rep. 2024; 14(1):6844.

PMID: 38514850 PMC: 10958006. DOI: 10.1038/s41598-024-57497-x.

Association of RDW, NLR, and PLR with Atrial Fibrillation in Critical Care Patients: A Retrospective Study Based on Propensity Score Matching.

Guan Y, Yin R, Zheng P, Liu C, Wei B, Deng G Dis Markers. 2022; 2022:2694499.

PMID: 35669502 PMC: 9166973. DOI: 10.1155/2022/2694499.

A Review of Biomarkers for Ischemic Stroke Evaluation in Patients With Non-valvular Atrial Fibrillation.

Shang L, Zhang L, Guo Y, Sun H, Zhang X, Bo Y Front Cardiovasc Med. 2021; 8:682538.

PMID: 34277733 PMC: 8281032. DOI: 10.3389/fcvm.2021.682538.

Biomarkers for Predicting Left Atrial or Left Atrial Appendage Thrombus in Anticoagulated Patients with Nonvalvular Atrial Fibrillation.

Zhou X, Wang Z, Dou S, Chen K, Liu E, Liu T Cardiol Res Pract. 2020; 2020:1683142.

PMID: 32655946 PMC: 7322584. DOI: 10.1155/2020/1683142.

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