Maedi-Visna Virus: Current Perspectives

Overview

Journal Vet Med (Auckl)

Specialty Veterinary Medicine

Date 2018 Jul 28

PMID 30050863

Citations 27

Authors

Esperanza Gomez-Lucia

Nuria Barquero

Ana Domenech

Affiliations

Soon will be listed here.

Abstract

Maedi-Visna virus (MVV) and caprine arthritis-encephalitis virus are commonly known as small ruminant lentiviruses (SRLVs) due to their genetic, structural, and pathogenic similarities. They produce lifelong lasting infections in their hosts, which are characterized by slow progression till overt disease happens. There are four major clinical forms derived from a chronic inflammatory response due to the constant low grade production of viruses from monocyte-derived macrophages: respiratory (caused by interstitial pneumonia), mammary (which may produce a decrease in milk production due to subclinical mastitis), joint (characterized by lameness), and neurological (characterized by chronic nonpurulent meningoencephalomyelitis). There are three levels which try to eliminate the virus: cellular, body, and the flock level. However, SRLVs have ways to counteract these defenses. This review examines some of them.

Citing Articles

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Molecular Characterization of Small Ruminant Lentiviruses in Sheep and Goats: A Systematic Review.

Gobbi P, Pavone S, Orso M, Passamonti F, Righi C, Beato M Animals (Basel). 2024; 14(23).

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Identification of concurrent infection with Jaagsiekte sheep retrovirus and maedi-visna virus in China.

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Distribution of maedi-visna virus in different organs of the spontaneously affected small ruminants in India.

Valecha S, Yadav H, Roopa N, Vinaykumar S, Bhardwaj M, Singh V Iran J Vet Res. 2024; 25(1):41-47.

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Differential gene expression and immune cell infiltration in maedi-visna virus-infected lung tissues.

Shi X, Zhang Y, Chen S, Du X, Zhang P, Duan X BMC Genomics. 2024; 25(1):534.

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