Identification of Periprosthetic Joint Infection After Total Hip Arthroplasty

Overview

Journal J Orthop Translat

Publisher Elsevier

Specialty Orthopedics

Date 2018 Jul 24

PMID 30035036

Citations 10

Authors

Kyung-Jae Lee

Stuart B Goodman

Affiliations

Soon will be listed here.

Abstract

Although total hip arthroplasty (THA) is accepted as one of the most successful surgical procedures in orthopaedic surgery, periprosthetic joint infection after THA continues to be one of the most devastating complications. However, accurate preoperative identification of periprosthetic joint infection in patients presenting with joint pain or radiographic periprosthetic lucencies is often difficult, even after a comprehensive work-up. The purpose of this article is to review the diagnostic options available to improve the management and results of this potentially catastrophic complication.

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References

Parvizi J, Ghanem E, Menashe S, Barrack R, Bauer T . Periprosthetic infection: what are the diagnostic challenges?. J Bone Joint Surg Am. 2006; 88 Suppl 4:138-47. DOI: 10.2106/JBJS.F.00609. View

Fehring T, Cohen B . Aspiration as a guide to sepsis in revision total hip arthroplasty. J Arthroplasty. 1996; 11(5):543-7. DOI: 10.1016/s0883-5403(96)80107-0. View

Spangehl M, Masri B, OConnell J, Duncan C . Prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg Am. 1999; 81(5):672-83. DOI: 10.2106/00004623-199905000-00008. View

Lachiewicz P, Rogers G, Thomason H . Aspiration of the hip joint before revision total hip arthroplasty. Clinical and laboratory factors influencing attainment of a positive culture. J Bone Joint Surg Am. 1996; 78(5):749-54. DOI: 10.2106/00004623-199605000-00015. View

Callaghan J, Bracha P, Liu S, Piyaworakhun S, Goetz D, Johnston R . Survivorship of a Charnley total hip arthroplasty. A concise follow-up, at a minimum of thirty-five years, of previous reports. J Bone Joint Surg Am. 2009; 91(11):2617-21. DOI: 10.2106/JBJS.H.01201. View

Squire M, Della Valle C, Parvizi J . Preoperative diagnosis of periprosthetic joint infection: role of aspiration. AJR Am J Roentgenol. 2011; 196(4):875-9. DOI: 10.2214/AJR.10.5160. View

Schinsky M, Della Valle C, Sporer S, Paprosky W . Perioperative testing for joint infection in patients undergoing revision total hip arthroplasty. J Bone Joint Surg Am. 2008; 90(9):1869-75. DOI: 10.2106/JBJS.G.01255. View

Caton J, Prudhon J . Over 25 years survival after Charnley's total hip arthroplasty. Int Orthop. 2011; 35(2):185-8. PMC: 3032109. DOI: 10.1007/s00264-010-1197-z. View

Zmistowski B, Parvizi J . Identification and treatment of infected total hip arthroplasty. Expert Rev Anti Infect Ther. 2012; 10(4):509-18. DOI: 10.1586/eri.12.19. View

10.

Deirmengian C, Kardos K, Kilmartin P, Cameron A, Schiller K, Parvizi J . Diagnosing periprosthetic joint infection: has the era of the biomarker arrived?. Clin Orthop Relat Res. 2014; 472(11):3254-62. PMC: 4182392. DOI: 10.1007/s11999-014-3543-8. View

11.

Greidanus N, Masri B, Garbuz D, Wilson S, McAlinden M, Xu M . Use of erythrocyte sedimentation rate and C-reactive protein level to diagnose infection before revision total knee arthroplasty. A prospective evaluation. J Bone Joint Surg Am. 2007; 89(7):1409-16. DOI: 10.2106/JBJS.D.02602. View

12.

Chryssikos T, Parvizi J, Ghanem E, Newberg A, Zhuang H, Alavi A . FDG-PET imaging can diagnose periprosthetic infection of the hip. Clin Orthop Relat Res. 2008; 466(6):1338-42. PMC: 2384031. DOI: 10.1007/s11999-008-0237-0. View

13.

Perry J, Reed M, Sprowson A, Rankin K, Refaie R . The assessment of neutrophil CD64 count as an early warning marker of joint replacement infection. Arch Orthop Trauma Surg. 2013; 133(10):1351-8. DOI: 10.1007/s00402-013-1816-4. View

14.

Randau T, Friedrich M, Wimmer M, Reichert B, Kuberra D, Stoffel-Wagner B . Interleukin-6 in serum and in synovial fluid enhances the differentiation between periprosthetic joint infection and aseptic loosening. PLoS One. 2014; 9(2):e89045. PMC: 3931684. DOI: 10.1371/journal.pone.0089045. View

15.

Neut D, van Horn J, van Kooten T, van der Mei H, Busscher H . Detection of biomaterial-associated infections in orthopaedic joint implants. Clin Orthop Relat Res. 2003; (413):261-8. DOI: 10.1097/01.blo.0000073345.50837.84. View

16.

Cahir J, Toms A, Marshall T, Wimhurst J, Nolan J . CT and MRI of hip arthroplasty. Clin Radiol. 2007; 62(12):1163-71. DOI: 10.1016/j.crad.2007.04.018. View

17.

Fitzgerald Jr R, Nolan D, Ilstrup D, Van Scoy R, Washington 2nd J, COVENTRY M . Deep wound sepsis following total hip arthroplasty. J Bone Joint Surg Am. 1977; 59(7):847-55. View

18.

Berbari E, Mabry T, Tsaras G, Spangehl M, Erwin P, Murad M . Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg Am. 2010; 92(11):2102-9. DOI: 10.2106/JBJS.I.01199. View

19.

Pulido L, Ghanem E, Joshi A, Purtill J, Parvizi J . Periprosthetic joint infection: the incidence, timing, and predisposing factors. Clin Orthop Relat Res. 2008; 466(7):1710-5. PMC: 2505241. DOI: 10.1007/s11999-008-0209-4. View

20.

Barrack R, Jennings R, Wolfe M, Bertot A . The Coventry Award. The value of preoperative aspiration before total knee revision. Clin Orthop Relat Res. 1998; (345):8-16. View