Treatment For The Large Aggressive Benign Lesions Of The Jaws

Overview

Journal J Maxillofac Oral Surg

Date 2018 Jul 24

PMID 30034157

Citations 2

Authors

Sirmahan Cakarer

S Cemil Isler

Basak Keskin

Aysenur Uzun

Hulya Kocak Berberoglu

Cengizhan Keskin

Affiliations

Soon will be listed here.

Abstract

Objectives: Our aim was to evaluate the clinical outcome of the conservative management of the significantly large benign aggressive lesions of the jaws.

Subjects And Methods: Twenty-two patients were reviewed regarding the demographic, radiographic, and operative findings. Patients were treated by decompression followed by curettage or only with curettage.

Results: No bone grafts were used. Mean follow-up time was 56.2 months. The mandible was more affected than the maxilla. Two of the ameloblastoma, two of the keratocystic odontogenic tumours, and one odontogenic myxoma were recurred.

Conclusions: Despite the low number of the patients, it is concluded that the conservative management is predictable for the management of the benign aggressive lesions in order to reduce morbidity instead of directly performing radical surgery. The life during follow-up is mandatory in the situation of performing conservative surgery for the management of large aggressive lesions with high recurrence rate.

Citing Articles

Evaluating Treatment Modalities for Reducing Recurrence in Central Giant Cell Granuloma: A Narrative Review.

Aliu F, Shabani D, Aliu I, Qeli E, Kacani G, Fiorillo L Dent J (Basel). 2024; 12(9).

PMID: 39329860 PMC: 11431665. DOI: 10.3390/dj12090295.

Application of ultrasound in aggressive angiomyxoma: Eight case reports and review of literature.

Zhao C, Su N, Jiang Y, Yang M World J Clin Cases. 2018; 6(14):811-819.

PMID: 30510948 PMC: 6264985. DOI: 10.12998/wjcc.v6.i14.811.

References

Kinard B, Chuang S, August M, Dodson T . How well do we manage the odontogenic keratocyst?. J Oral Maxillofac Surg. 2013; 71(8):1353-8. DOI: 10.1016/j.joms.2013.01.029. View

Kumar V . Conservative surgical approach to aggressive benign odontogenic neoplasm: a report of three cases. J Korean Assoc Oral Maxillofac Surg. 2015; 41(1):37-42. PMC: 4347036. DOI: 10.5125/jkaoms.2015.41.1.37. View

Zhou H, Hou R, Ma Q, Wu K, Ding Y, Qin R . Secondary healing after removal of large keratocystic odontogenic tumor in the mandible: enucleation followed by open packing of iodoform gauze. J Oral Maxillofac Surg. 2012; 70(7):1523-30. DOI: 10.1016/j.joms.2011.12.021. View

Schlieve T, Miloro M, Kolokythas A . Does decompression of odontogenic cysts and cystlike lesions change the histologic diagnosis?. J Oral Maxillofac Surg. 2014; 72(6):1094-105. DOI: 10.1016/j.joms.2013.12.028. View

Chiapasco M, Rossi A, Motta J, Crescentini M . Spontaneous bone regeneration after enucleation of large mandibular cysts: a radiographic computed analysis of 27 consecutive cases. J Oral Maxillofac Surg. 2000; 58(9):942-8; discussion 949. DOI: 10.1053/joms.2000.8732. View

Liang Y, He W, Zheng P, Liao G . Inferior alveolar nerve function recovers after decompression of large mandibular cystic lesions. Oral Dis. 2015; 21(5):674-8. DOI: 10.1111/odi.12338. View

Bansal S, Desai R, Shirsat P, Prasad P, Karjodkar F, Andrade N . The occurrence and pattern of ameloblastoma in children and adolescents: an Indian institutional study of 41 years and review of the literature. Int J Oral Maxillofac Surg. 2015; 44(6):725-31. DOI: 10.1016/j.ijom.2015.01.002. View

Guimaraes A, Dutra de Cassia Ferreira Santos M, de Carvalho G, Chone C, Nizam Pfeilsticker L . Giant keratocystic odontogenic tumor: three cases and literature review. Iran J Otorhinolaryngol. 2013; 25(73):245-52. PMC: 3846250. View

Johnson N, Batstone M, Savage N . Management and recurrence of keratocystic odontogenic tumor: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012; 116(4):e271-6. DOI: 10.1016/j.oooo.2011.12.028. View

10.

Servato J, Prieto-Oliveira P, de Faria P, Loyola A, Cardoso S . Odontogenic tumours: 240 cases diagnosed over 31 years at a Brazilian university and a review of international literature. Int J Oral Maxillofac Surg. 2012; 42(2):288-93. DOI: 10.1016/j.ijom.2012.05.008. View

11.

Anthony Pogrel M, Jordan R . Marsupialization as a definitive treatment for the odontogenic keratocyst. J Oral Maxillofac Surg. 2004; 62(6):651-5. DOI: 10.1016/j.joms.2003.08.029. View

12.

Ihan Hren N, Miljavec M . Spontaneous bone healing of the large bone defects in the mandible. Int J Oral Maxillofac Surg. 2008; 37(12):1111-6. DOI: 10.1016/j.ijom.2008.07.008. View

13.

Pogrel M . The keratocystic odontogenic tumour (KCOT)--an odyssey. Int J Oral Maxillofac Surg. 2015; 44(12):1565-8. DOI: 10.1016/j.ijom.2015.03.008. View

14.

Ebenezer V, Ramalingam B . Importance of Different Modalities of Treatment For the Management of Keratocystic Odontogenic Tumour with Five year follow-up. J Clin Diagn Res. 2014; 8(3):225-8. PMC: 4003650. DOI: 10.7860/JCDR/2014/7486.4168. View

15.

Lahey E, Woo S, Park H . Odontogenic myxoma with diffuse calcifications: a case report and review of the literature. Head Neck Pathol. 2012; 7(1):97-102. PMC: 3597162. DOI: 10.1007/s12105-012-0387-y. View

16.

Dandriyal R, Gupta A, Pant S, Baweja H . Surgical management of ameloblastoma: Conservative or radical approach. Natl J Maxillofac Surg. 2012; 2(1):22-7. PMC: 3304226. DOI: 10.4103/0975-5950.85849. View

17.

Zecha J, Amaral Mendes R, Lindeboom V, van der Waal I . Recurrence rate of keratocystic odontogenic tumor after conservative surgical treatment without adjunctive therapies - A 35-year single institution experience. Oral Oncol. 2010; 46(10):740-2. DOI: 10.1016/j.oraloncology.2010.07.004. View

18.

de Molon R, Verzola M, Pires L, Mascarenhas V, da Silva R, Cirelli J . Five years follow-up of a keratocyst odontogenic tumor treated by marsupialization and enucleation: A case report and literature review. Contemp Clin Dent. 2015; 6(Suppl 1):S106-10. PMC: 4374304. DOI: 10.4103/0976-237X.152963. View

19.

Xavier S, De Mello-Filho F, Rodrigues W, Sonoda C, de Melo W . Conservative approach: using decompression procedure for management of a large unicystic ameloblastoma of the mandible. J Craniofac Surg. 2014; 25(3):1012-4. DOI: 10.1097/SCS.0000000000000716. View