Increased Sugar Transport in BHK Cells Infected with Semliki Forest Virus or with Herpes Simplex Virus

Overview

Journal Arch Virol

Specialty Microbiology

Date 1986 Jan 1

PMID 3002302

Citations 4

Authors

M A Gray

M H James

J C BOOTH

C A Pasternak

Affiliations

Soon will be listed here.

Abstract

Infection of BHK cells by SFV increases the rate of uptake of [3H]MeGlc and of [3H]dGlc at approximately 2 hours p.i. Infection by HSV increases the uptake of [3H]MeGlc and [3H]dGlc at approximately 10 hours p.i.; the increased uptake is prevented by acyclovir. It is concluded that an increased sugar uptake by infected cells reflects an increased rate of transport across the plasma membrane and is the result of cellular changes caused by virus infection.

Citing Articles

Investigation of cell culture conditions for optimal foot-and-mouth disease virus production.

Dill V, Zimmer A, Beer M, Eschbaumer M BMC Biotechnol. 2019; 19(1):33.

PMID: 31174517 PMC: 6555971. DOI: 10.1186/s12896-019-0527-5.

Nutritional demands and metabolic characteristics of the DSIR-HA-1179 insect cell line during growth and infection with the Oryctes nudivirus.

Pushparajan C, Claus J, Marshall S, Visnovsky G In Vitro Cell Dev Biol Anim. 2017; 53(10):908-921.

PMID: 29197034 DOI: 10.1007/s11626-017-0206-6.

Analysis of epithelial cell stress response during infection by Shigella flexneri.

Mantis N, Prevost M, Sansonetti P Infect Immun. 1996; 64(7):2474-82.

PMID: 8698469 PMC: 174100. DOI: 10.1128/iai.64.7.2474-2482.1996.

Membrane transport and disease.

Pasternak C Mol Cell Biochem. 1989; 91(1-2):3-11.

PMID: 2560140 DOI: 10.1007/BF00228073.

References

Foster K, Micklem K, Agnarsdottir G, Lancashire C, BOGOMOLOVA N, Boriskin Y . Myxoviruses do not induce non-specific alterations in membrane permeability early on in infection. Arch Virol. 1983; 77(2-4):139-53. DOI: 10.1007/BF01309263. View

Decker S, LIPMANN F . Transport of D-glucose by membrane vesicles from normal and avian sarcoma virus-transformed chicken embryo fibroblasts. Proc Natl Acad Sci U S A. 1981; 78(9):5358-61. PMC: 348744. DOI: 10.1073/pnas.78.9.5358. View

White M, BRAMWELL M, Harris H . Kinetic parameters of hexose transport in hybrids between malignant and nonmalignant cells. J Cell Sci. 1983; 62:49-80. DOI: 10.1242/jcs.62.1.49. View

Romano A . Is glucose transport enhanced in virus-transformed mammalian cells? A dissenting view. J Cell Physiol. 1976; 89(4):737-44. DOI: 10.1002/jcp.1040890434. View

Stinski M . Synthesis of proteins and glycoproteins in cells infected with human cytomegalovirus. J Virol. 1977; 23(3):751-67. PMC: 515887. DOI: 10.1128/JVI.23.3.751-767.1977. View

Eisenthal R, Cornish-Bowden A . The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters. Biochem J. 1974; 139(3):715-20. PMC: 1166335. DOI: 10.1042/bj1390715. View

Carrasco L, Lacal J . Permeabilization of cells during animal virus infection. Pharmacol Ther. 1983; 23(1):109-45. DOI: 10.1016/0163-7258(83)90028-1. View

Carrasco L, Smith A . Molecular biology of animal virus infection. Pharmacol Ther. 1980; 9(3):311-55. DOI: 10.1016/0163-7258(80)90022-4. View

Schultz S, Curran P . Coupled transport of sodium and organic solutes. Physiol Rev. 1970; 50(4):637-718. DOI: 10.1152/physrev.1970.50.4.637. View

10.

Plagemann P . Deoxyglucose transport of uninfected, murine sarcoma virus-transformed, and murine leukemia virus-infected mouse cells. J Cell Physiol. 1973; 82(3):421-33. DOI: 10.1002/jcp.1040820312. View

11.

Antoniades H, Owen A . Growth factors and regulation of cell growth. Annu Rev Med. 1982; 33:445-63. DOI: 10.1146/annurev.me.33.020182.002305. View

12.

Wohlhueter R, Plagemann P . The roles of transport and phosphorylation in nutrient uptake in cultured animal cells. Int Rev Cytol. 2010; 64:171-240. DOI: 10.1016/s0074-7696(08)60238-7. View

13.

Martin G, Venuta S, Weber M, Rubin H . Temperature-dependent alterations in sugar transport in cells infected by a temperature-sensitive mutant of Rous sarcoma virus. Proc Natl Acad Sci U S A. 1971; 68(11):2739-41. PMC: 389513. DOI: 10.1073/pnas.68.11.2739. View

14.

Peluso R, Lamb R, Choppin P . Infection with paramyxoviruses stimulates synthesis of cellular polypeptides that are also stimulated in cells transformed by Rous sarcoma virus or deprived of glucose. Proc Natl Acad Sci U S A. 1978; 75(12):6120-4. PMC: 393130. DOI: 10.1073/pnas.75.12.6120. View

15.

Hatanaka M, HUEBNER R, Gilden R . Alterations in the characteristics of sugar uptake by mouse cells transformed by murine sarcoma viruses. J Natl Cancer Inst. 1969; 43(5):1091-6. View

16.

Isselbacher K . Increased uptake of amino acids and 2-deoxy-D-glucose by virus-transformed cells in culture. Proc Natl Acad Sci U S A. 1972; 69(3):585-9. PMC: 426512. DOI: 10.1073/pnas.69.3.585. View

17.

White M, BRAMWELL M, Harris H . Hexose transport in hybrids between malignant and normal cells. Nature. 1981; 294(5838):232-5. DOI: 10.1038/294232a0. View

18.

Jeor S, Albrecht T, Funk F, Rapp F . Stimulation of cellular DNA synthesis by human cytomegalovirus. J Virol. 1974; 13(2):353-62. PMC: 355304. DOI: 10.1128/JVI.13.2.353-362.1974. View

19.

Weber M, Evans P, Johnson M, McNair T, Nakamura K, Salter D . Transport of potassium, amino acids, and glucose in cells transformed by Rous sarcoma virus. Fed Proc. 1984; 43(1):107-12. View

20.

Gray M, Micklem K, Pasternak C . Protein synthesis in cells infected with Semliki Forest virus is not controlled by intracellular cation changes. Eur J Biochem. 1983; 135(2):299-302. DOI: 10.1111/j.1432-1033.1983.tb07652.x. View