One Environmental Health: an Emerging Perspective in Toxicology

Overview

Journal F1000Res

Specialties Biomedical Engineering
Science

Date 2018 Jul 14

PMID 30002815

Citations 9

Authors

Adam Perez

John Pierce Wise Sr

Affiliations

Soon will be listed here.

Abstract

The One Environmental Health research approach, a subspecialty of the One Health initiative, focuses on toxic chemicals. Distinct disciplines work together to give a holistic perspective of a health concern through discrete disciplines, including, but not limited to, public health and the medical and veterinary sciences. In this article, we illustrate the concept of One Environmental Health with two case studies. One case study focuses on alligators and contributions to the field of endocrine disruption. The other case study focuses on whales and contributions to understanding carcinogenic metals. Both studies illustrate how the health of sentinel organisms has the potential to inform about the health of humans and the ecosystem.

Citing Articles

One health: a structured review and commentary on trends and themes.

Brown H, Pursley I, Horton D, La Ragione R One Health Outlook. 2024; 6(1):17.

PMID: 39138554 PMC: 11323492. DOI: 10.1186/s42522-024-00111-x.

Elevated Metal Levels in U.S. Honeys: Is There a Concern for Human Health?.

Wise Jr J, Wise R, Hoffert A, Wise J, Specht A Biol Trace Elem Res. 2024; .

PMID: 38995435 PMC: 11816500. DOI: 10.1007/s12011-024-04295-1.

A whale of a tale: whale cells evade the driving mechanism for hexavalent chromium-induced chromosome instability.

Lu H, Toyoda J, Wise S, Browning C, Speer R, Croom-Perez T Toxicol Sci. 2024; 199(1):49-62.

PMID: 38539048 PMC: 11057468. DOI: 10.1093/toxsci/kfae030.

A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health.

Rupprecht B, Wise Sr J, Reynolds M CourseSource. 2023; 9.

PMID: 37711997 PMC: 10501411. DOI: 10.24918/cs.2022.30.

Blood concentrations of per- and polyfluoroalkyl substances are associated with autoimmune-like effects in American alligators from Wilmington, North Carolina.

Guillette T, Jackson T, Guillette M, McCord J, Belcher S Front Toxicol. 2022; 4:1010185.

PMID: 36337916 PMC: 9630345. DOI: 10.3389/ftox.2022.1010185.

References

Uzumcu M, Zama A, Oruc E . Epigenetic mechanisms in the actions of endocrine-disrupting chemicals: gonadal effects and role in female reproduction. Reprod Domest Anim. 2012; 47 Suppl 4:338-47. PMC: 4151320. DOI: 10.1111/j.1439-0531.2012.02096.x. View

Kristensen D, Skalkam M, Audouze K, Lesne L, Desdoits-Lethimonier C, Frederiksen H . Many putative endocrine disruptors inhibit prostaglandin synthesis. Environ Health Perspect. 2010; 119(4):534-41. PMC: 3080937. DOI: 10.1289/ehp.1002635. View

Bossart G . Marine mammals as sentinel species for oceans and human health. Vet Pathol. 2010; 48(3):676-90. DOI: 10.1177/0300985810388525. View

Moore B, Roark A, Kohno S, Hamlin H, Guillette Jr L . Gene-environment interactions: the potential role of contaminants in somatic growth and the development of the reproductive system of the American alligator. Mol Cell Endocrinol. 2011; 354(1-2):111-20. PMC: 3328103. DOI: 10.1016/j.mce.2011.10.020. View

Milnes M, Bryan T, Katsu Y, Kohno S, Moore B, Iguchi T . Increased posthatching mortality and loss of sexually dimorphic gene expression in alligators (Alligator mississippiensis) from a contaminated environment. Biol Reprod. 2008; 78(5):932-8. DOI: 10.1095/biolreprod.107.064915. View

Newman S, Smith S . Marine mammal neoplasia: a review. Vet Pathol. 2006; 43(6):865-80. DOI: 10.1354/vp.43-6-865. View

Panigada S, Pesante G, Zanardelli M, Capoulade F, Gannier A, Weinrich M . Mediterranean fin whales at risk from fatal ship strikes. Mar Pollut Bull. 2006; 52(10):1287-98. DOI: 10.1016/j.marpolbul.2006.03.014. View

Norman R, Dewailly D, Legro R, Hickey T . Polycystic ovary syndrome. Lancet. 2007; 370(9588):685-97. DOI: 10.1016/S0140-6736(07)61345-2. View

Wise J, Wise S, Kraus S, Shaffiey F, Grau M, Chen T . Hexavalent chromium is cytotoxic and genotoxic to the North Atlantic right whale (Eubalaena glacialis) lung and testes fibroblasts. Mutat Res. 2007; 650(1):30-8. DOI: 10.1016/j.mrgentox.2007.09.007. View

10.

Browning C, Qin Q, Kelly D, Prakash R, Vanoli F, Jasin M . Prolonged Particulate Hexavalent Chromium Exposure Suppresses Homologous Recombination Repair in Human Lung Cells. Toxicol Sci. 2016; 153(1):70-8. PMC: 5601504. DOI: 10.1093/toxsci/kfw103. View

11.

Oumeish O . The philosophical, cultural, and historical aspects of complementary, alternative, unconventional, and integrative medicine in the Old World. Arch Dermatol. 1998; 134(11):1373-86. DOI: 10.1001/archderm.134.11.1373. View

12.

Witmer C, Park H, Shupack S . Mutagenicity and disposition of chromium. Sci Total Environ. 1989; 86(1-2):131-48. DOI: 10.1016/0048-9697(89)90200-3. View

13.

Guillette Jr L, Crain D, Rooney A, Pickford D . Organization versus activation: the role of endocrine-disrupting contaminants (EDCs) during embryonic development in wildlife. Environ Health Perspect. 1995; 103 Suppl 7:157-64. PMC: 1518862. DOI: 10.1289/ehp.95103s7157. View

14.

Wise Sr J, Payne R, Wise S, Lacerte C, Wise J, Gianios Jr C . A global assessment of chromium pollution using sperm whales (Physeter macrocephalus) as an indicator species. Chemosphere. 2009; 75(11):1461-7. DOI: 10.1016/j.chemosphere.2009.02.044. View

15.

Zinsstag J, Schelling E, Waltner-Toews D, Tanner M . From "one medicine" to "one health" and systemic approaches to health and well-being. Prev Vet Med. 2010; 101(3-4):148-56. PMC: 3145159. DOI: 10.1016/j.prevetmed.2010.07.003. View

16.

Guillette Jr L, Gross T, Gross D, Rooney A, Percival H . Gonadal steroidogenesis in vitro from juvenile alligators obtained from contaminated or control lakes. Environ Health Perspect. 1995; 103 Suppl 4:31-6. PMC: 1519267. DOI: 10.1289/ehp.95103s431. View

17.

Li H, Chen Q, Li S, Yao W, Li L, Shi X . Effect of Cr(VI) exposure on sperm quality: human and animal studies. Ann Occup Hyg. 2001; 45(7):505-11. View

18.

Guillette Jr L, Gross T, Masson G, Matter J, Percival H, Woodward A . Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ Health Perspect. 1994; 102(8):680-8. PMC: 1567320. DOI: 10.1289/ehp.94102680. View

19.

Savery L, Chen T, Wise J, Wise S, Gianios Jr C, Buonagurio J . Global assessment of cadmium concentrations in the skin of free-ranging sperm whales (Physeter macrocephalus). Comp Biochem Physiol C Toxicol Pharmacol. 2015; 178:136-144. DOI: 10.1016/j.cbpc.2015.09.012. View

20.

Crain D, Guillette Jr L, Rooney A, Pickford D . Alterations in steroidogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants. Environ Health Perspect. 1997; 105(5):528-33. PMC: 1469881. DOI: 10.1289/ehp.97105528. View