[Alterations of Respiratory Resistance in Patients with Obstructive Sleep Apnea Hypopnea Syndrome]

Overview

Journal Nan Fang Yi Ke Da Xue Xue Bao

Specialty General Medicine

Date 2018 Jul 13

PMID 29997103

Citations 2

Authors

Ze-Chuan Cai

Tao-Ping Li

Xiao-Xia Lu

Yu-Feng Wang

Xiao Wang

Ting Xu

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the association between the components of airway resistance and severity of obstructive sleep apnea hypopnea syndrome (OSAHS).

Methods: A total of 234 patients with snoring during sleep underwent full-night polysomnography in our center between January, 2015 and September, 2017. According to the apnea-hypopnea index (AHI) scores, the patients were divided into non-OSAHS group (AHI scores <5), mild or moderate OSAHS group (5-30) group, and severe OSAHS group (>30). The pulmonary function and respiratory resistance of the patients were assessed using spirometry and impulse oscillometry, respectively, and the correlation between the parameters of respiratory resistance and the severity of AHI were analyzed.

Results: The non-OSAHS, mild or moderate OSAHS, and severe OSAHS groups consisted of 31, 90 and 113 patients, respectively. The patients with severe OSAHS had significantly higher levels of respiratory resistance at 5 Hz (R5) and 20 Hz (R20), FEF and MMEF than those in the other two groups (P<0.05). Bivariate correlation analysis identified positive correlations of R5 (r=0.259, P=0.000), R20 (r=0.298, P=0.000) and FEF (r=0.176, P=0.007) with AHI scores of the patients.

Conclusion: Patients with OSAHS have increased respiratory resistance in the large airways and compensatory reduction in small airway resistance.

Citing Articles

Small airway resistance in obese and nonobese patients with obstructive sleep apnea syndrome using impulse oscillometry.

Gungordu N, Ismayilova A, Aliyeva N, Alhelou T, Ozdil Eser A, Vardaloglu Koyuncu I Turk J Med Sci. 2024; 54(2):441-448.

PMID: 39050388 PMC: 11265845. DOI: 10.55730/1300-0144.5809.

Research on the Association Between Obstructive Sleep Apnea Hypopnea Syndrome Complicated With Coronary Heart Disease and Inflammatory Factors, Glycolipid Metabolism, Obesity, and Insulin Resistance.

Wen Y, Zhang H, Tang Y, Yan R Front Endocrinol (Lausanne). 2022; 13:854142.

PMID: 35846285 PMC: 9283718. DOI: 10.3389/fendo.2022.854142.

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