Antimicrobial Activity of Five Essential Oils Against Bacteria and Fungi Responsible for Urinary Tract Infections

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2018 Jul 11

PMID 29987237

Citations 28

Authors

Valentina Virginia Ebani

Simona Nardoni

Fabrizio Bertelloni

Luisa Pistelli

Francesca Mancianti

Affiliations

Soon will be listed here.

Abstract

Urinary tract infections are frequently encountered in small animal practice. and spp. are the most common agents associated to these infections, even though other bacteria and yeasts, such as and may be involved. In view of the increasing problem of the multi-drug resistance, the aim of this study was to investigate the antimicrobial activity of essential oils obtained from star anise ( Hook.f.), basil ( L.), origanum ( L.), clary sage ( L.) and thymus ( L.) against multidrug-resistant strains of , spp., and previously isolated from dogs and cats with urinary tract infections. Enterococci were resistant to and , such as to . and essential oils showed the best activity against all the tested pathogens, so they could be proposed for the formulation of external and/or intravesical washes in small animals.

Citing Articles

Isolation, characterization and antimicrobial activity study of Thymus vulgaris.

Wirtu S, Ramaswamy K, Maitra R, Chopra S, Kumar Mishra A, Jule L Sci Rep. 2024; 14(1):21573.

PMID: 39284874 PMC: 11405399. DOI: 10.1038/s41598-024-71012-2.

Enhancing Antibiotic Efficacy and Combating Biofilm Formation: Evaluating the Synergistic Potential of Essential Oil against Multidrug-Resistant Gram-Negative Bacteria.

Saoudi B, Bariz K, Saci S, Belounis Y, Issad H, Abbaci M Microorganisms. 2024; 12(8).

PMID: 39203493 PMC: 11356740. DOI: 10.3390/microorganisms12081651.

The Antimicrobial Effect of L. and L. Fruit Extracts against Resistant Uropathogens in Correlation with the Prevalence of Urinary Tract Infections in Companion Animals.

Aurori M, Novac C, Nadas G, Craciun S, Fit N, Andrei S Pharmaceuticals (Basel). 2024; 17(6).

PMID: 38931481 PMC: 11206431. DOI: 10.3390/ph17060814.

L. (Star Anise) Essential Oil: GC/MS Profile, Molecular Docking Study, In Silico ADME Profiling, Quorum Sensing, and Biofilm-Inhibiting Effect on Foodborne Bacteria.

Noumi E, Ahmad I, Adnan M, Patel H, Merghni A, Haddaji N Molecules. 2023; 28(23).

PMID: 38067422 PMC: 10707387. DOI: 10.3390/molecules28237691.

In-vitro Antimicrobial Study of Non/irradiated Ylang-ylang Essential Oil Against Multi Drug Resistant Pathogens with Reference to Microscopic Morphological Alterations.

Elkenawy N, Soliman M, El-Behery R Indian J Microbiol. 2023; 63(4):621-631.

PMID: 38034904 PMC: 10682331. DOI: 10.1007/s12088-023-01122-4.

References

Vanden Bossche H, Marichal P, Gorrens J, Bellens D, Moereels H, Janssen P . Mutation in cytochrome P-450-dependent 14 alpha-demethylase results in decreased affinity for azole antifungals. Biochem Soc Trans. 1990; 18(1):56-9. DOI: 10.1042/bst0180056. View

Nardoni S, Giovanelli S, Pistelli L, Mugnaini L, Profili G, Pisseri F . In Vitro Activity of Twenty Commercially Available, Plant-Derived Essential Oils against Selected Dermatophyte Species. Nat Prod Commun. 2015; 10(8):1473-8. View

Braga P, Dal Sasso M, Culici M, Alfieri M . Eugenol and thymol, alone or in combination, induce morphological alterations in the envelope of Candida albicans. Fitoterapia. 2007; 78(6):396-400. DOI: 10.1016/j.fitote.2007.02.022. View

Huang Y, Zhao J, Zhou L, Wang J, Gong Y, Chen X . Antifungal activity of the essential oil of Illicium verum fruit and its main component trans-anethole. Molecules. 2010; 15(11):7558-69. PMC: 6259245. DOI: 10.3390/molecules15117558. View

Fisher J, Sobel J, Kauffman C, Newman C . Candida urinary tract infections--treatment. Clin Infect Dis. 2011; 52 Suppl 6:S457-66. DOI: 10.1093/cid/cir112. View

Rex J, Rinaldi M, Pfaller M . Resistance of Candida species to fluconazole. Antimicrob Agents Chemother. 1995; 39(1):1-8. PMC: 162475. DOI: 10.1128/AAC.39.1.1. View

Hawrelak J, Cattley T, Myers S . Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study. Altern Med Rev. 2009; 14(4):380-4. View

Ghorbani A, Esmaeilizadeh M . Pharmacological properties of and its components. J Tradit Complement Med. 2017; 7(4):433-440. PMC: 5634728. DOI: 10.1016/j.jtcme.2016.12.014. View

Ahmad A, Khan A, Akhtar F, Yousuf S, Xess I, Khan L . Fungicidal activity of thymol and carvacrol by disrupting ergosterol biosynthesis and membrane integrity against Candida. Eur J Clin Microbiol Infect Dis. 2010; 30(1):41-50. DOI: 10.1007/s10096-010-1050-8. View

10.

Bandeira Reidel R, Melai B, Cioni P, Flamini G, Pistelli L . Aroma Profile of Rubus ulmifolius Flowers and Fruits During Different Ontogenetic Phases. Chem Biodivers. 2016; 13(12):1776-1784. DOI: 10.1002/cbdv.201600170. View

11.

De M, De A, Sen P, Banerjee A . Antimicrobial properties of star anise (Illicium verum Hook f). Phytother Res. 2002; 16(1):94-5. DOI: 10.1002/ptr.989. View

12.

Sanguinetti M, Posteraro B, Lass-Florl C . Antifungal drug resistance among Candida species: mechanisms and clinical impact. Mycoses. 2015; 58 Suppl 2:2-13. DOI: 10.1111/myc.12330. View

13.

Willems N, Houwers D, Schlotter Y, Theelen B, Boekhout T . Disseminated Candidiasis in a Young, Previously Healthy, Dog and Review of Literature. Mycopathologia. 2016; 182(5-6):591-596. PMC: 5425501. DOI: 10.1007/s11046-016-0092-6. View

14.

Jin Y, Lin D . Fungal urinary tract infections in the dog and cat: a retrospective study (2001-2004). J Am Anim Hosp Assoc. 2005; 41(6):373-81. DOI: 10.5326/0410373. View

15.

Pietrella D, Angiolella L, Vavala E, Rachini A, Mondello F, Ragno R . Beneficial effect of Mentha suaveolens essential oil in the treatment of vaginal candidiasis assessed by real-time monitoring of infection. BMC Complement Altern Med. 2011; 11:18. PMC: 3056850. DOI: 10.1186/1472-6882-11-18. View

16.

Papon N, Courdavault V, Clastre M, Bennett R . Emerging and emerged pathogenic Candida species: beyond the Candida albicans paradigm. PLoS Pathog. 2013; 9(9):e1003550. PMC: 3784480. DOI: 10.1371/journal.ppat.1003550. View

17.

Wang G, Hu W, Huang B, Qin L . Illicium verum: a review on its botany, traditional use, chemistry and pharmacology. J Ethnopharmacol. 2011; 136(1):10-20. DOI: 10.1016/j.jep.2011.04.051. View

18.

Ahmad A, Khan A, Manzoor N . Reversal of efflux mediated antifungal resistance underlies synergistic activity of two monoterpenes with fluconazole. Eur J Pharm Sci. 2012; 48(1-2):80-6. DOI: 10.1016/j.ejps.2012.09.016. View

19.

Benmalek Y, Yahia O, Belkebir A, Fardeau M . Anti-microbial and anti-oxidant activities of Illicium verum, Crataegus oxyacantha ssp monogyna and Allium cepa red and white varieties. Bioengineered. 2013; 4(4):244-8. PMC: 3728195. DOI: 10.4161/bioe.24435. View

20.

Kuzma L, Kalemba D, Rozalski M, Rozalska B, Wieckowska-Szakiel M, Krajewska U . Chemical composition and biological activities of essential oil from Salvia sclarea plants regenerated in vitro. Molecules. 2009; 14(4):1438-47. PMC: 6254371. DOI: 10.3390/molecules14041438. View