Pulmonary Tuberculosis in a Male with Silicosis
Overview
Pulmonary Medicine
Affiliations
Silicosis, a preventable occupational lung disease, is associated with various diseases, including tuberculosis (TB). There is an increased lifelong risk for lung tuberculosis even if exposure to silica dust ceases. That association contributes in a large extent to very high rates of tuberculosis in countries with poor TB and silica exposure control. We report a case of a male with a prior diagnosis of silicosis who was diagnosed with and treated for TB. Anti-tuberculous treatment was extended due to a positive sputum smear in the six th month of treatment. However, the culture of the sputum was negative. This case report highlights the value of thorough screening for tuberculosis in silicotic patients. The clinical management of these patients may be challenging due to frequent overlapping radiological features and uncertain results of TB treatment.
Sarkar B, Sarkar K J Biol Methods. 2025; 11(4):e99010035.
PMID: 39839089 PMC: 11744064. DOI: 10.14440/jbm.2024.0053.
Silicotuberculosis: a critical narrative review.
Ehrlich R, Murray J, Said-Hartley Q, Rees D Eur Respir Rev. 2024; 33(174).
PMID: 39694587 PMC: 11668511. DOI: 10.1183/16000617.0168-2024.
Silicosis-Allergic Bronchopulmonary Aspergillosis Overlap-A Rare Duet!.
Neenu N, Utpat K, Desai U, Samuel M, Bagul R, Shah H Indian J Occup Environ Med. 2024; 28(1):86-89.
PMID: 38783879 PMC: 11111145. DOI: 10.4103/ijoem.ijoem_170_23.
A Complex Case of Pulmonary Silico-Tuberculosis and Review of Literature.
DSa L, Pezzuto F, Lunardi F, Scalvenzi F, Tine M, Comacchio G Diagnostics (Basel). 2023; 13(17).
PMID: 37685266 PMC: 10486577. DOI: 10.3390/diagnostics13172728.
Luhadia K, Yashi K, Virk J, Parikh T, Goyal L, Alam A Cureus. 2023; 15(2):e35425.
PMID: 36999113 PMC: 10044064. DOI: 10.7759/cureus.35425.